SNS-032 (BMS-387032)
Also known as: 1-diMethylethyl)-2-oxazolyl]Methyl]thio]-2-thiazolyl], 4-Piperidinecarboxamide, N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-, 4-Piperidinecarboxamide,N-(5-(((5-(1,1-dimethylethyl)-2-oxazolyl)methyl)thio)-2-thiazolyl), BMS 387032, BMS-3870032, BMS-3870032 N-[5-[(5-tert-Butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide, BMS-387032, BMS387032, CS-202, N-(5-(((5-(1,1-dimethylethyl)-2-oxazolyl)methyl)thio)-2-thiazolyl)-4-piperidinecarboxamide, N-(5-((5-Tert-Butyloxazol-2-yl)methylthio)thiazol-2-yl)piperidine-4-carboxamide, N-(5-{[(5-tert-Butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)piperidine-4-carboxamide, N-[5-({[5-(2-Methyl-2-propanyl)-1,3-oxazol-2-yl]methyl}sulfanyl)-1,3-thiazol-2-yl]-4-piperidinecarboxamide, N-[5-[(5-tert-Butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide SNS-032 (BMS-387032), N-[5-[(5-tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamid, N-[5-[(5-tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide, N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide, SNS 032, SNS-032, 98.5%, a selective CDK2 inhibitor, SNS-032, >=99%
SNS-032 (BMS-387032) (CAS 345627-80-7) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C17H24N4O2S2 and a molecular weight of 380.528 g/mol. Key property: a density of 1.3±0.1 g/cm3. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 345627-80-7
- Jingsj CID
- J-1955106-5
- Molecular Formula
- C17H24N4O2S2
- Molecular Weight
- 380.528 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Exact Mass | 380.134064 |
| PSA | 133.59000 |
| LogP | 2.79 |
| Refractive Index | 1.607 |
| Storage Conditions | -20℃ |
Activity & Biological Data
| Target | CDK9:4 nM (IC50) CDK2:38 nM (IC50) CDK7:62 nM (IC50) CDK1:480 nM (IC50) CDK4:925 nM (IC50) |
|---|---|
| Additional Information | [1]. Chen R, et al. Mechanism of action of SNS-032, a novel cyclin-dependent kinase inhibitor, in chronic lymphocytic leukemia. Blood. 2009 May 7;113(19):4637-45. [2]. Ali MA, et al. SNS-032 prevents tumor cell-induced angiogenesis by inhibiting vascular endothelial growth factor. Neoplasia. 2007 May;9(5):370-81. [3]. Conroy A, et al. SNS-032 is a potent and selective CDK 2, 7 and 9 inhibitor that drives target modulation in patient samples. Cancer Chemother Pharmacol. 2009 Sep;64(4):723-32. [4]. Wu Y, et al. Cyclin-dependent kinase 7/9 inhibitor SNS-032 abrogates FIP1-like-1 platelet-derived growth factor receptor α and bcr-abl oncogene addiction in malignant hematologic cells.Clin Cancer Res. 2012 Apr 1;18(7):1966-78. Epub 2012 Mar 23. [5]. Walsby E, et al. The cyclin-dependent kinase inhibitor SNS-032 has single agent activity in AML cells and is highly synergistic with cytarabine.Leukemia. 2011 Mar;25(3):411-9. Epub 2011 Jan 7. |
Frequently Asked Questions
What is the CAS number of SNS-032 (BMS-387032)?
The CAS number of SNS-032 (BMS-387032) is 345627-80-7.
What are the molecular formula and molecular weight of SNS-032 (BMS-387032)?
SNS-032 (BMS-387032) has molecular formula C17H24N4O2S2 and molecular weight 380.528 g/mol.
What are the upstream and downstream products of SNS-032 (BMS-387032)?
For SNS-032 (BMS-387032), Upstream Products: 1-Bromopinacolone, 5-tert-Butyl-2-(chloromethyl)oxazole, 5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-amine.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "SNS-032 (BMS-387032) (CAS 345627-80-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1955106-5 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.