Tropisetron

Also known as: ICS 205-930, Navoban, SDZ-ICS-930, 1H-Indole-3-carboxylic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, end-1H-Indole-3-carboxylic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester

Tropisetron (CAS 89565-68-4) is a compound in the Aliphatic Hydrocarbons category listed in the Jingsj chemical database. It has the molecular formula C17H20N2O2 and a molecular weight of 284.35 g/mol. Key properties include a melting point of 201-202 °C, a boiling point of 448.5±35.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 225.0±25.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 89565-68-4
Jingsj CID: J-18940-2
Molecular Formula: C₁₇H₂₀N₂O₂
Molecular Weight: 284.35 g/mol
Category: Aliphatic Hydrocarbons
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	201-202 °C
Boiling Point	448.5±35.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	225.0±25.9 °C
PSA	83.80000
LogP	3.55
Vapor Pressure	0.0±1.1 mmHg at 25°C
Refractive Index	1.644
Storage Conditions	2-8°C
Additional Property	H2O: soluble

Activity & Biological Data

Additional Information	[1]. Macor JE, et al. The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective alpha7 nicotinic receptor partial agonist. Bioorg Med Chem Lett. 2001 Feb 12;11(3):319-21. [2]. Vega Lde L, et al. The 5-HT3 receptor antagonist tropisetron inhibits T cell activation by targeting the calcineurin pathway. Biochem Pharmacol. 2005 Aug 1;70(3):369-80. [3]. Stratz C, et al. The anti-inflammatory effects of the 5-HT? receptor antagonist tropisetron are mediated by the inhibition of p38 MAPK activation in primary human monocytes. Int Immunopharmacol. 2012 Aug;13(4):398-402. [4]. Candelario-Jalil E, et al. Detrimental effects of tropisetron on permanent ischemic stroke in the rat. BMC Neurosci. 2008 Feb 6;9:19.

Additional Information

[1]. Macor JE, et al. The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective alpha7 nicotinic receptor partial agonist. Bioorg Med Chem Lett. 2001 Feb 12;11(3):319-21. [2]. Vega Lde L, et al. The 5-HT3 receptor antagonist tropisetron inhibits T cell activation by targeting the calcineurin pathway. Biochem Pharmacol. 2005 Aug 1;70(3):369-80. [3]. Stratz C, et al. The anti-inflammatory effects of the 5-HT? receptor antagonist tropisetron are mediated by the inhibition of p38 MAPK activation in primary human monocytes. Int Immunopharmacol. 2012 Aug;13(4):398-402. [4]. Candelario-Jalil E, et al. Detrimental effects of tropisetron on permanent ischemic stroke in the rat. BMC Neurosci. 2008 Feb 6;9:19.

Frequently Asked Questions

What is the CAS number of Tropisetron?

The CAS number of Tropisetron is 89565-68-4.

What are the molecular formula and molecular weight of Tropisetron?

Tropisetron has molecular formula C17H20N2O2 and molecular weight 284.35 g/mol.

What are the upstream and downstream products of Tropisetron?

For Tropisetron, Upstream Products: 1H-indole-3-carbonyl chloride, Tropine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Tropisetron (CAS 89565-68-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-18940-2 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.