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8-Hydroxyquinoline-5-carboxylic acid

Also known as: 5-Carboxy-8-hydroxyquinoline, 5-Quinolinecarboxylic acid, 8-hydroxy-, 8-Hydroxy-5-quinolinecarboxylic acid, 8-Hydroxy-chinolin-5-carbonsaeure, 8-hydroxy-quinoline-5-carboxylic acid, 8XQ, IOX1, UNII-JM015YQC1C

8-Hydroxyquinoline-5-carboxylic acid (CAS 5852-78-8) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C10H7NO3 and a molecular weight of 189.167 g/mol. Key properties include a boiling point of 464.5±30.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 234.7±24.6 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
5852-78-8
Jingsj CID
J-1656-8
Molecular Formula
C10H7NO3
Molecular Weight
189.167 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point464.5±30.0 °C at 760 mmHg
Density1.5±0.1 g/cm3
Flash Point234.7±24.6 °C
Exact Mass189.042587
PSA70.42000
LogP1.81
Appearancewhite to brown
Vapor Pressure0.0±1.2 mmHg at 25°C
Refractive Index1.730
Storage Conditions2-8°C
Additional PropertyDMSO: soluble10mg/mL, clear

GHS Safety & Compliance

IrritantSignal word: Warning
  • H302 — Harmful if swallowed

Activity & Biological Data

Additional Information[1]. Schiller R, et al. A cell-permeable ester derivative of the JmjC histone demethylase inhibitor IOX1. ChemMedChem. 2014 Mar;9(3):566-71.

Customs & Trade Information

HS Code2933499090
Summary2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 8-Hydroxyquinoline-5-carboxylic acid?

The CAS number of 8-Hydroxyquinoline-5-carboxylic acid is 5852-78-8.

What are the molecular formula and molecular weight of 8-Hydroxyquinoline-5-carboxylic acid?

8-Hydroxyquinoline-5-carboxylic acid has molecular formula C10H7NO3 and molecular weight 189.167 g/mol.

Is 8-Hydroxyquinoline-5-carboxylic acid hazardous?

8-Hydroxyquinoline-5-carboxylic acid has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.

What are the upstream and downstream products of 8-Hydroxyquinoline-5-carboxylic acid?

For 8-Hydroxyquinoline-5-carboxylic acid, Upstream Products: 3-Amino-4-hydroxybenzoic acid, Acrolein, 8-Hydroxyquinoline; Downstream Products: 2,3-Pyridinedicarboxylic acid, 8-Hydroxyquinoline.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "8-Hydroxyquinoline-5-carboxylic acid (CAS 5852-78-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1656-8 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.