4,5,6,7-Tetrabromo-1H-benzotriazole
Also known as: TBB, TBBt, NSC 231634, 4,5,6,7-Tetrabromo-2-azabenzimidazole, Casein kinase II inhibitor TBB, 1H-1,2,3-Benzotriazole, 4,5,6,7-tetrabromo-, 1H-Benzotriazole,4,5,6,7-tetrabromo-
4,5,6,7-Tetrabromo-1H-benzotriazole (CAS 17374-26-4) is a compound in the Aromatic Hydrocarbons category listed in the Jingsj chemical database. It has the molecular formula C6HBr4N3 and a molecular weight of 434.708 g/mol. Key properties include a melting point of 262-266ºC, a boiling point of 552.5±45.0 °C at 760 mmHg, a density of 2.8±0.1 g/cm3 and a flash point of 288.0±28.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 17374-26-4
- Jingsj CID
- J-1518412-2
- Molecular Formula
- C6HBr4N3
- Molecular Weight
- 434.708 g/mol
- Category
- Aromatic Hydrocarbons
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 262-266ºC |
|---|---|
| Boiling Point | 552.5±45.0 °C at 760 mmHg |
| Density | 2.8±0.1 g/cm3 |
| Flash Point | 288.0±28.7 °C |
| Exact Mass | 430.690369 |
| PSA | 41.57000 |
| LogP | 3.96 |
| Vapor Pressure | 0.0±1.5 mmHg at 25°C |
| Refractive Index | 1.801 |
Activity & Biological Data
| Target | CK2:0.15 μM (IC50, Human CK2) PIM1:1.04 μM (IC50) PIM2:4.3 μM (IC50) PIM3:0.86 μM (IC50) HIPK2:5.3 μM (IC50) HIPK3:4.9 μM (IC50) DYRK1a:4.36 μM (IC50) DYRK2:0.99 μM (IC50) DYRK3:5.3 μM (IC50) PKD1:5.9 μM (IC50) CDK2:14 μM (IC50) |
|---|---|
| Additional Information | [1]. De Moliner E, et al. Alternative binding modes of an inhibitor to two different kinases. Eur J Biochem. 2003 Aug;270(15):3174-81. [2]. Orzechowska E, et al. Time schedule-dependent effect of the CK2 inhibitor TBB on PC-3 human prostate cancer cell viability. Oncol Rep. 2012 Jan;27(1):281-5. [3]. Sarno S, et al. Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2'). FEBS Lett. 2001 May 4;496(1):44-8. [4]. Ljubimov AV, et al. Involvement of protein kinase CK2 in angiogenesis and retinal neovascularization. Invest Ophthalmol Vis Sci. 2004 Dec;45(12):4583-91. [5]. Pagano MA, et al. The selectivity of inhibitors of protein kinase CK2: an update. Biochem J. 2008 Nov 1;415(3):353-65. [6]. Chen Z, et al. CK2α promotes advanced glycation end products-induced expressions of fibronectin and intercellular adhesion molecule-1 via activating MRTF-A in glomerular mesangial cells. Biochem Pharmacol. 2017 Dec 6;148:41-51. |
Customs & Trade Information
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of 4,5,6,7-Tetrabromo-1H-benzotriazole?
The CAS number of 4,5,6,7-Tetrabromo-1H-benzotriazole is 17374-26-4.
What are the molecular formula and molecular weight of 4,5,6,7-Tetrabromo-1H-benzotriazole?
4,5,6,7-Tetrabromo-1H-benzotriazole has molecular formula C6HBr4N3 and molecular weight 434.708 g/mol.
What are the upstream and downstream products of 4,5,6,7-Tetrabromo-1H-benzotriazole?
For 4,5,6,7-Tetrabromo-1H-benzotriazole, Upstream Products: 1H-Benzotriazole.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "4,5,6,7-Tetrabromo-1H-benzotriazole (CAS 17374-26-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1518412-2 (accessed 2026-11-07).
Data for reference only; verify product details with suppliers before purchase.