Cortisone acetate

Also known as: Cortisone 21-acetate, 11-Dehydro-17-hydroxycorticosterone 21-acetate, 17α,21-Dihydroxy-4-pregnene-3,11,20-trione 21-acetate, 21-Acetoxy-17α-hydroxypregn-4-ene-3,11,20-trione, 4-Pregnene-17α,21-diol-3,11,20-trione 21-acetate, Acetic acid 2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl ester, Cortisone, 21-acetate, 17α,21-Dihydroxypregn-4-ene-3,11,20-trione 21-acetate, Cortisone (acetate)

Cortisone acetate (CAS 50-04-4) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C23H30O6 and a molecular weight of 402.481 g/mol. Key properties include a melting point of 237-240 °C(lit.), a boiling point of 577.3±50.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 197.3±23.6 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 50-04-4
Jingsj CID: J-15076-5
Molecular Formula: C₂₃H₃₀O₆
Molecular Weight: 402.481 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	237-240 °C(lit.)
Boiling Point	577.3±50.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	197.3±23.6 °C
Exact Mass	402.204254
PSA	97.74000
LogP	2.53
Vapor Pressure	0.0±3.6 mmHg at 25°C
Refractive Index	1.566

Activity & Biological Data

Additional Information	[1]. Hirano T, et al. Cortisone counteracts apoptosis-inducing effect of cortisol in human peripheral-blood mononuclear cells. Int Immunopharmacol. 2001 Nov;1(12):2109-15. [2]. Chan J, et al. Glucocorticoid-induced apoptosis in human decidua: a novel role for 11beta-hydroxysteroid dehydrogenase in late gestation. J Endocrinol. 2007 Oct;195(1):7-15. [3]. Rusu VM, et al. In vivo effects of cortisone on the B cell line in chickens. J Immunol. 1975 Nov;115(5):1370-4. [4]. Kisch AL, et al. Synergistic nephrotoxicity of amphotericin B and cortisone acetate in mice. J Infect Dis. 1978 Jun;137(6):789-94.

Additional Information

[1]. Hirano T, et al. Cortisone counteracts apoptosis-inducing effect of cortisol in human peripheral-blood mononuclear cells. Int Immunopharmacol. 2001 Nov;1(12):2109-15. [2]. Chan J, et al. Glucocorticoid-induced apoptosis in human decidua: a novel role for 11beta-hydroxysteroid dehydrogenase in late gestation. J Endocrinol. 2007 Oct;195(1):7-15. [3]. Rusu VM, et al. In vivo effects of cortisone on the B cell line in chickens. J Immunol. 1975 Nov;115(5):1370-4. [4]. Kisch AL, et al. Synergistic nephrotoxicity of amphotericin B and cortisone acetate in mice. J Infect Dis. 1978 Jun;137(6):789-94.

Frequently Asked Questions

What is the CAS number of Cortisone acetate?

The CAS number of Cortisone acetate is 50-04-4.

What are the molecular formula and molecular weight of Cortisone acetate?

Cortisone acetate has molecular formula C23H30O6 and molecular weight 402.481 g/mol.

What are the upstream and downstream products of Cortisone acetate?

For Cortisone acetate, Upstream Products: Hydrocortisone acetate, Hydrocortisone, acetic acid; Downstream Products: Adrenosterone, Hydrocortisone, Prednisone 21-acetate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Cortisone acetate (CAS 50-04-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-15076-5 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.