N-Boc-trans-4-hydroxy-L-proline methyl ester
Also known as: Boc-Hyp-OMe, BOC-HYP-OME, 1-tert-Butyl 2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate, N-Boc-4-hydroxy-L-proline methyl ester, Boc-L-Hyp-OMe, N-(tert-Butoxycarbonyl)-trans-4-hydroxy-L-proline methyl ester, BOC-Hydroxyproline methyl ester
N-Boc-trans-4-hydroxy-L-proline methyl ester (CAS 74844-91-0) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C11H19NO5 and a molecular weight of 245.272 g/mol. Key properties include a melting point of 92-96 °C(lit.), a boiling point of 335.2±42.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 156.6±27.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 74844-91-0
- Jingsj CID
- J-14415-0
- Molecular Formula
- C11H19NO5
- Molecular Weight
- 245.272 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 92-96 °C(lit.) |
|---|---|
| Boiling Point | 335.2±42.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 156.6±27.9 °C |
| Exact Mass | 245.126328 |
| PSA | 76.07000 |
| LogP | -0.25 |
| Vapor Pressure | 0.0±1.6 mmHg at 25°C |
| Refractive Index | 1.501 |
Activity & Biological Data
| Target | Non-cleavable |
|---|---|
| Additional Information | [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337. [2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. |
Customs & Trade Information
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of N-Boc-trans-4-hydroxy-L-proline methyl ester?
The CAS number of N-Boc-trans-4-hydroxy-L-proline methyl ester is 74844-91-0.
What are the molecular formula and molecular weight of N-Boc-trans-4-hydroxy-L-proline methyl ester?
N-Boc-trans-4-hydroxy-L-proline methyl ester has molecular formula C11H19NO5 and molecular weight 245.272 g/mol.
What are the upstream and downstream products of N-Boc-trans-4-hydroxy-L-proline methyl ester?
For N-Boc-trans-4-hydroxy-L-proline methyl ester, Upstream Products: Di-tert-butyl dicarbonate, L-4-Hydroxyproline methyl ester hydrochloride, Boc-L-Hydroxyproline; Downstream Products: (2S,4R)-Boc-4-phenyl-pyrrolidine-2-carboxylic acid, cis-N-Boc-4-cyano-L-proline methyl ester, (2S,4S)-1-(tert-Butoxycarbonyl)-4-(2-naphthyloxy)pyrrolidine-2-carboxylic acid.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "N-Boc-trans-4-hydroxy-L-proline methyl ester (CAS 74844-91-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-14415-0 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.