1-[bis(4-fluorophenyl)methyl]piperazine

Also known as: 1-(4,4'-difluorobenzhydryl)piperazine, 1-(4,4'-difluorodiphenylmethyl)piperazine, 1-bis(4-fluorophenyl)methylpiperazine, N-[bis(4-fluorophenyl)methyl]piperazine, 4,4'-difluorobenzhydrylpiperazine, flunarizine impurity A, 1-[bis(p-fluorophenyl)methyl]piperazine

1-[bis(4-fluorophenyl)methyl]piperazine (CAS 27469-60-9) is a compound in the Aromatic Hydrocarbons category listed in the Jingsj chemical database. It has the molecular formula C17H18F2N2 and a molecular weight of 288.335 g/mol. Key properties include a melting point of 88-92 °C(lit.), a boiling point of 367.9±37.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 176.3±26.5 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 27469-60-9
Jingsj CID: J-1334605-9
Molecular Formula: C₁₇H₁₈F₂N₂
Molecular Weight: 288.335 g/mol
Category: Aromatic Hydrocarbons
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	88-92 °C(lit.)
Boiling Point	367.9±37.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	176.3±26.5 °C
Exact Mass	288.143799
PSA	15.27000
LogP	2.95
Vapor Pressure	0.0±0.8 mmHg at 25°C
Refractive Index	1.560
Additional Property	0.34 g/L (20 ºC)

GHS Safety & Compliance

Acute ToxicitySignal word: Danger

H301 — Toxic if swallowed
H315 — Causes skin irritation
H319 — Causes serious eye irritation
H335 — May cause respiratory irritation

Frequently Asked Questions

What is the CAS number of 1-[bis(4-fluorophenyl)methyl]piperazine?

The CAS number of 1-[bis(4-fluorophenyl)methyl]piperazine is 27469-60-9.

What are the molecular formula and molecular weight of 1-[bis(4-fluorophenyl)methyl]piperazine?

1-[bis(4-fluorophenyl)methyl]piperazine has molecular formula C17H18F2N2 and molecular weight 288.335 g/mol.

Is 1-[bis(4-fluorophenyl)methyl]piperazine hazardous?

1-[bis(4-fluorophenyl)methyl]piperazine has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H315 — Causes skin irritation; H319 — Causes serious eye irritation.

What are the upstream and downstream products of 1-[bis(4-fluorophenyl)methyl]piperazine?

For 1-[bis(4-fluorophenyl)methyl]piperazine, Upstream Products: Piperazine, 4,4'-Difluorodiphenylmethylchloride, 4,4'-Difluorobenzhydrol; Downstream Products: Flunarizine, Almitrine, Lomerizine hydrochloride.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "1-[bis(4-fluorophenyl)methyl]piperazine (CAS 27469-60-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1334605-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.