Loreclezole

Also known as: Loreclezole, R 72063, R-72063, 1-[(Z)-2-chloro-2-(2,4-dichlorophenyl)ethenyl]-1H-1,2,4-triazole, 1-[(Z)-2-Chloro-2-(2,4-dichlorophenyl)ethenyl]-1,2,4-triazole, 1H-1,2,4-Triazole, 1-[(1Z)-2-chloro-2-(2,4-dichlorophenyl)ethenyl]-, Loreclezolum, Loreclezol, UNII-6DJ32STZ5W

Loreclezole (CAS 117857-45-1) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C10H6Cl3N3 and a molecular weight of 274.53 g/mol. Key properties include a boiling point of 418.7ºC at 760mmHg, a density of 1.48g/cm3 and a flash point of 207ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 117857-45-1
Jingsj CID: J-1320902-7
Molecular Formula: C₁₀H₆Cl₃N₃
Molecular Weight: 274.53 g/mol
Category: Organohalogen Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	418.7ºC at 760mmHg
Density	1.48g/cm3
Flash Point	207ºC
Exact Mass	272.96300
PSA	30.71000
LogP	3.77930
Vapor Pressure	3.23E-07mmHg at 25°C
Refractive Index	1.65
Storage Conditions	2-8℃

Activity & Biological Data

Target	GABAA receptor[1].
Additional Information	[1]. Wingrove PB, et al. The modulatory action of loreclezole at the gamma-aminobutyric acid type A receptor is determined by a single amino acid in the beta 2 and beta 3 subunit. Proc Natl Acad Sci U S A. 1994 May 10;91(10):4569-73. [2]. Sanna E, et al. Direct activation of GABAA receptors by loreclezole, an anticonvulsant drug with selectivity for the beta-subunit. Neuropharmacology. 1996;35(12):1753-60.

Target

GABAA receptor[1].

Additional Information

[1]. Wingrove PB, et al. The modulatory action of loreclezole at the gamma-aminobutyric acid type A receptor is determined by a single amino acid in the beta 2 and beta 3 subunit. Proc Natl Acad Sci U S A. 1994 May 10;91(10):4569-73. [2]. Sanna E, et al. Direct activation of GABAA receptors by loreclezole, an anticonvulsant drug with selectivity for the beta-subunit. Neuropharmacology. 1996;35(12):1753-60.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Loreclezole?

The CAS number of Loreclezole is 117857-45-1.

What are the molecular formula and molecular weight of Loreclezole?

Loreclezole has molecular formula C10H6Cl3N3 and molecular weight 274.53 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Loreclezole (CAS 117857-45-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1320902-7 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.