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Dihydroberberine

Also known as: 5,8-Dihydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine, 6H-1,3-Benzodioxolo[5,6-a]benzo[g]quinolizine, 5,8-dihydro-9,10-dimethoxy-, 9,10-Dimethoxy-2,3-(methylenedioxy)-13,13a-didehydroberbine, 9,10-Dimethoxy-5,8-dihydro-6H-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinoline, 9,10-Dimethoxy-6,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinoline, Dihydroberbine, Dihydroumbellatine, Nsc331264

Dihydroberberine (CAS 483-15-8) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C20H19NO4 and a molecular weight of 337.369 g/mol. Key properties include a melting point of 223-224ºC (dec.), a boiling point of 557.8±50.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 170.7±27.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
483-15-8
Jingsj CID
J-12952-2
Molecular Formula
C20H19NO4
Molecular Weight
337.369 g/mol
Category
Organic Bases
Last updated
8/21/2026

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Physicochemical Properties

Melting Point223-224ºC (dec.)
Boiling Point557.8±50.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point170.7±27.3 °C
Exact Mass337.131409
PSA40.16000
LogP5.09
Vapor Pressure0.0±1.5 mmHg at 25°C
Refractive Index1.679
Storage Conditions2-8C

Activity & Biological Data

TargetHSP90
Additional Information[1]. Yu D, et al. Inhibitory effects and mechanism of dihydroberberine on hERG channels expressed in HEK293 cells. PLoS One. 2017 Aug 1;12(8):e0181823.

Customs & Trade Information

HS Code2934999090
Summary2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Dihydroberberine?

The CAS number of Dihydroberberine is 483-15-8.

What are the molecular formula and molecular weight of Dihydroberberine?

Dihydroberberine has molecular formula C20H19NO4 and molecular weight 337.369 g/mol.

What are the upstream and downstream products of Dihydroberberine?

For Dihydroberberine, Upstream Products: Berberine hydrochloride, Tetrahydroberberine, 2,3-Dimethoxybenzaldehyde; Downstream Products: Berberine hydrochloride, Noroxyhydrastinine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Dihydroberberine (CAS 483-15-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-12952-2 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.