Trimethylamine N-oxide
Also known as: Trimethylamine oxide, TMAO, N,N-dimethylmethanamine N-oxide, N,N-dimethylmethanamine oxide, Trimethyloxamine, Triox, Trimethylamineoxid, Amine oxide, trimethyl-, EINECS 214-675-6, MFCD00002048, Methanamine,N,N-dimethyl-,N-oxide
Trimethylamine N-oxide (CAS 1184-78-7) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C3H9NO and a molecular weight of 75.110 g/mol. Key properties include a melting point of 220-222ºC(lit.), a boiling point of 133.8°C (rough estimate) and a density of 0.9301 (rough estimate). It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 1184-78-7
- Jingsj CID
- J-12060-5
- Molecular Formula
- C3H9NO
- Molecular Weight
- 75.110 g/mol
- Category
- Organic Bases
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 220-222ºC(lit.) |
|---|---|
| Boiling Point | 133.8°C (rough estimate) |
| Density | 0.9301 (rough estimate) |
| Exact Mass | 75.068413 |
| PSA | 29.43000 |
| LogP | -2.57 |
| Refractive Index | 1.4698 (estimate) |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Target | ROS/NLRP3 inflammasome[1] TGF-β/smad2[1] |
|---|---|
| Additional Information | [1]. Wei Shuai, et al. High-choline Diet Exacerbates Cardiac Dysfunction, Fibrosis, and Inflammation in a Mouse Model of Heart Failure With Preserved Ejection Fraction. J Card Fail. 2020 May 14;S1071-9164(19)31802-0. [2]. Wenlong Yang, et al. Gut Microbe-Derived Metabolite Trimethylamine N-oxide Accelerates Fibroblast-Myofibroblast Differentiation and Induces Cardiac Fibrosis. J Mol Cell Cardiol. 2019 Sep;134:119-130. [3]. Manuel T Velasquez, et al. Trimethylamine N-Oxide: The Good, the Bad and the Unknown. Toxins (Basel). 2016 Nov 8;8(11):326. |
Customs & Trade Information
| HS Code | 2921110090 |
|---|---|
| Summary | HS: 2921110090. methylamine, di- or trimethylamine and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:ab(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. general tariff:30.0% |
Frequently Asked Questions
What is the CAS number of Trimethylamine N-oxide?
The CAS number of Trimethylamine N-oxide is 1184-78-7.
What are the molecular formula and molecular weight of Trimethylamine N-oxide?
Trimethylamine N-oxide has molecular formula C3H9NO and molecular weight 75.110 g/mol.
Is Trimethylamine N-oxide hazardous?
Trimethylamine N-oxide has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of Trimethylamine N-oxide?
For Trimethylamine N-oxide, Upstream Products: Trimethylamine, Trimethylamine N-oxide dihydrate, Dimethyl sulfate; Downstream Products: N,N,2-trimethylpropan-1-amine, Isopropyl trifluoroacetate, (1-methylpyrrolidin-3-yl)methanol.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Trimethylamine N-oxide (CAS 1184-78-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-12060-5 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.