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tert-Butyl (3-((2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)carbamate

Also known as: N-[3-[[2-Chloro-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]carbamic acid 1,1-dimethylethyl ester, CO-1686 intermediate 3, CO1686 Intermediate2, ROCI-003, tert-butyl N-(3-{[2-chloro-5-(trifluoromethyl)pyrimidin-4-yl]amino}phenyl)carbamate, 2-Methyl-2-propanyl (3-{[2-chloro-5-(trifluoromethyl)-4-pyrimidinyl]amino}phenyl)carbamate, Carbamic acid, N-[3-[[2-chloro-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-, 1,1-dimethylethyl ester

tert-Butyl (3-((2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)carbamate (CAS 1374507-23-9) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C16H16ClF3N4O2 and a molecular weight of 388.772 g/mol. Key properties include a boiling point of 446.2±45.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 223.6±28.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
1374507-23-9
Jingsj CID
J-1169805-8
Molecular Formula
C16H16ClF3N4O2
Molecular Weight
388.772 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point446.2±45.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point223.6±28.7 °C
Exact Mass388.091400
PSA76.14000
LogP5.53
Vapor Pressure0.0±1.1 mmHg at 25°C
Refractive Index1.577

Frequently Asked Questions

What is the CAS number of tert-Butyl (3-((2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)carbamate?

The CAS number of tert-Butyl (3-((2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)carbamate is 1374507-23-9.

What are the molecular formula and molecular weight of tert-Butyl (3-((2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)carbamate?

tert-Butyl (3-((2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)carbamate has molecular formula C16H16ClF3N4O2 and molecular weight 388.772 g/mol.

What are the upstream and downstream products of tert-Butyl (3-((2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)carbamate?

For tert-Butyl (3-((2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)carbamate, Downstream Products: Rociletinib.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "tert-Butyl (3-((2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)carbamate (CAS 1374507-23-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1169805-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.