trans-4-(tert-Butyldiphenylsilyloxy)-L-proline

Also known as: (2S,4R)-4-(tert-Butyldiphenylsilyloxy)pyrrolidine-2-carboxylic Acid, (2S,4R)-4-[tert-butyl(diphenyl)silyl]oxypyrrolidine-2-carboxylic acid, (4R)-4-(tert-Butyldiphenylsilyloxy)-L-proline, O-TBDPS-proline, L-Proline, 4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-, (4R)-

trans-4-(tert-Butyldiphenylsilyloxy)-L-proline (CAS 259212-61-8) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C21H27NO3Si and a molecular weight of 369.530 g/mol. Key properties include a melting point of 198 °C(dec.), a boiling point of 468.8±45.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 237.3±28.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 259212-61-8
Jingsj CID: J-1134609-1
Molecular Formula: C₂₁H₂₇NO₃Si
Molecular Weight: 369.530 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	198 °C(dec.)
Boiling Point	468.8±45.0 °C at 760 mmHg
Density	1.1±0.1 g/cm3
Flash Point	237.3±28.7 °C
Exact Mass	369.176025
PSA	58.56000
LogP	5.23
Vapor Pressure	0.0±1.2 mmHg at 25°C
Refractive Index	1.574

Frequently Asked Questions

What is the CAS number of trans-4-(tert-Butyldiphenylsilyloxy)-L-proline?

The CAS number of trans-4-(tert-Butyldiphenylsilyloxy)-L-proline is 259212-61-8.

What are the molecular formula and molecular weight of trans-4-(tert-Butyldiphenylsilyloxy)-L-proline?

trans-4-(tert-Butyldiphenylsilyloxy)-L-proline has molecular formula C21H27NO3Si and molecular weight 369.530 g/mol.

What are the upstream and downstream products of trans-4-(tert-Butyldiphenylsilyloxy)-L-proline?

For trans-4-(tert-Butyldiphenylsilyloxy)-L-proline, Upstream Products: tert-Butyl(chloro)diphenylsilane, L-Hydroxyproline, (2S,4R)-Dibenzyl 4-hydroxypyrrolidine-1,2-dicarboxylate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "trans-4-(tert-Butyldiphenylsilyloxy)-L-proline (CAS 259212-61-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1134609-1 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.