Tenofovir

Also known as: (R)-PMPA, GS-1278, (R)-9-(2-Phosphonomethoxypropyl)adenine, [[(1R)-2(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic acid, 9-Pmpa, Apropovir

Tenofovir (CAS 147127-20-6) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C9H14N5O4P and a molecular weight of 287.212 g/mol. Key properties include a melting point of 276-280°C, a boiling point of 616.1±65.0 °C at 760 mmHg, a density of 1.8±0.1 g/cm3 and a flash point of 326.4±34.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 147127-20-6
Jingsj CID: J-1109276-5
Molecular Formula: C₉H₁₄N₅O₄P
Molecular Weight: 287.212 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	276-280°C
Boiling Point	616.1±65.0 °C at 760 mmHg
Density	1.8±0.1 g/cm3
Flash Point	326.4±34.3 °C
Exact Mass	287.078339
PSA	146.19000
LogP	-1.71
Vapor Pressure	0.0±1.9 mmHg at 25°C
Refractive Index	1.740
Storage Conditions	Store at -20°C
Additional Property	13.4 mg/mL (25 ºC)

Activity & Biological Data

Additional Information	[1]. Murphy RA, et al. Establishment of HK-2 Cells as a Relevant Model to Study Tenofovir-Induced Cytotoxicity. Int J Mol Sci. 2017 Mar 1;18(3). [2]. Musumeci G, et al. M48U1 and Tenofovir combination synergistically inhibits HIV infection in activated PBMCs and human cervicovaginal histocultures. Sci Rep. 2017 Feb 1;7:41018. [3]. Wahl A, et al. Predicting HIV Pre-exposure Prophylaxis Efficacy for Women using a Preclinical Pharmacokinetic-Pharmacodynamic In Vivo Model. Sci Rep. 2017 Feb 1;7:41098. [4]. Menne S, Cote PJ, Korba BE, Antiviral effect of oral administration of tenofovir disoproxil fumarate in woodchucks with chronic woodchuck hepatitis virus infection. Antimicrob Agents Chemother. 2005 Jul;49(7):2720-8.

Additional Information

[1]. Murphy RA, et al. Establishment of HK-2 Cells as a Relevant Model to Study Tenofovir-Induced Cytotoxicity. Int J Mol Sci. 2017 Mar 1;18(3). [2]. Musumeci G, et al. M48U1 and Tenofovir combination synergistically inhibits HIV infection in activated PBMCs and human cervicovaginal histocultures. Sci Rep. 2017 Feb 1;7:41018. [3]. Wahl A, et al. Predicting HIV Pre-exposure Prophylaxis Efficacy for Women using a Preclinical Pharmacokinetic-Pharmacodynamic In Vivo Model. Sci Rep. 2017 Feb 1;7:41098. [4]. Menne S, Cote PJ, Korba BE, Antiviral effect of oral administration of tenofovir disoproxil fumarate in woodchucks with chronic woodchuck hepatitis virus infection. Antimicrob Agents Chemother. 2005 Jul;49(7):2720-8.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Tenofovir?

The CAS number of Tenofovir is 147127-20-6.

What are the molecular formula and molecular weight of Tenofovir?

Tenofovir has molecular formula C9H14N5O4P and molecular weight 287.212 g/mol.

What are the upstream and downstream products of Tenofovir?

For Tenofovir, Upstream Products: (R)-9-[2-(DIETHYLPHOSPHONOMETHOXY)PROPYL]ADENINE, Diethyl (tosyloxy)methylphosphonate, (R)-(+)-9-(2-Hydroxypropyl)adenine; Downstream Products: Tenofovir Disoproxil Fumarate, Tenofovir alafenamide.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Tenofovir (CAS 147127-20-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1109276-5 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.