L-5-Hydroxytryptophan
Also known as: L-5-HTP, Oxitriptan, 5-Hydroxy-L-tryptophan, (-)-5-Hydroxy-L-tryptophan, L-2-Amino-3-(5-hydroxyindolyl)propionic acid, 2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid, Cincofarm, Levothym, Oxyfan, Serotonyl, Telesol, Pretonine
L-5-Hydroxytryptophan (CAS 4350-09-8) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C11H12N2O3 and a molecular weight of 220.22 g/mol. Key properties include a melting point of 270 °C (dec.)(lit.), a boiling point of 520.6±50.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 268.7±30.1 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 4350-09-8
- Jingsj CID
- J-1102081-8
- Molecular Formula
- C11H12N2O3
- Molecular Weight
- 220.22 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 270 °C (dec.)(lit.) |
|---|---|
| Boiling Point | 520.6±50.0 °C at 760 mmHg |
| Density | 1.5±0.1 g/cm3 |
| Flash Point | 268.7±30.1 °C |
| Exact Mass | 220.084793 |
| PSA | 99.34000 |
| LogP | -0.14 |
| Vapor Pressure | 0.0±1.4 mmHg at 25°C |
| Refractive Index | 1.737 |
| Additional Property | Slightly soluble |
GHS Safety & Compliance
- H301 — Toxic if swallowed
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Target | Human Endogenous Metabolite |
|---|---|
| Additional Information | [1]. ARVID CARLSSON, et al. 3,4-Dihydroxyphenylalanine and 5-Hydroxytryptophan as Reserpine Antagonists. Nature 180, page1200 (1957). [2]. Caruso I, et al. Double-blind study of 5-hydroxytryptophan versus placebo in the treatment of primary fibromyalgia syndrome. J Int Med Res. 1990 May-Jun;18(3):201-9. [3]. Thal LJ, et al. Treatment of myoclonus with L-5-hydroxytryptophan and carbidopa: clinical, electrophysiological, and biochemical observations. Ann Neurol. 1980 Jun;7(6):570-6. [4]. Boiardi A, et al. 5-OH-Tryptophane in migraine: clinical and neurophysiological considerations. J Neurol. 1981;225(1):41-6. [5]. Trouillas P, et al. Improvement of cerebellar ataxia with levorotatory form of 5-hydroxytryptophan. A double-blind study with quantified data processing. Arch Neurol. 1988 Nov;45(11):1217-22. |
Customs & Trade Information
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of L-5-Hydroxytryptophan?
The CAS number of L-5-Hydroxytryptophan is 4350-09-8.
What are the molecular formula and molecular weight of L-5-Hydroxytryptophan?
L-5-Hydroxytryptophan has molecular formula C11H12N2O3 and molecular weight 220.22 g/mol.
Is L-5-Hydroxytryptophan hazardous?
L-5-Hydroxytryptophan has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H315 — Causes skin irritation; H319 — Causes serious eye irritation.
What are the upstream and downstream products of L-5-Hydroxytryptophan?
For L-5-Hydroxytryptophan, Upstream Products: L-Tryptophan, 5-Hydroxyindole, L-Serine; Downstream Products: Serotonin, Boc-5-hydroxy-L-tryptophan.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "L-5-Hydroxytryptophan (CAS 4350-09-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1102081-8 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.