5-Hydroxyindole
Also known as: 1H-Indol-5-ol, 5-Indolol, 5-Hydroxy-1H-indole, Indol-5-ol, 1H-indole-5-ol
5-Hydroxyindole (CAS 1953-54-4) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C8H7NO and a molecular weight of 133.147 g/mol. Key properties include a melting point of 105-110ºC, a boiling point of 343.2±15.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 161.4±20.4 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 1953-54-4
- Jingsj CID
- J-34685-0
- Molecular Formula
- C8H7NO
- Molecular Weight
- 133.147 g/mol
- Category
- Pharma Intermediates
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 105-110ºC |
|---|---|
| Boiling Point | 343.2±15.0 °C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 161.4±20.4 °C |
| Exact Mass | 133.052765 |
| PSA | 36.02000 |
| LogP | 0.97 |
| Vapor Pressure | 0.0±0.8 mmHg at 25°C |
| Refractive Index | 1.739 |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Additional Information | [1]. Kooyman AR, et, al. 5-Hydroxyindole slows desensitization of the 5-HT3 receptor-mediated ion current in N1E-115 neuroblastoma cells. Br J Pharmacol. 1993 Feb;108(2):287-9. [2]. LaPorte M, et, al. 5-Hydroxyindoles by intramolecular alkynol-furan diels-alder cycloaddition. J Org Chem. 2013 Jan 4;78(1):167-74. |
|---|
Customs & Trade Information
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of 5-Hydroxyindole?
The CAS number of 5-Hydroxyindole is 1953-54-4.
What are the molecular formula and molecular weight of 5-Hydroxyindole?
5-Hydroxyindole has molecular formula C8H7NO and molecular weight 133.147 g/mol.
Is 5-Hydroxyindole hazardous?
5-Hydroxyindole has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of 5-Hydroxyindole?
For 5-Hydroxyindole, Upstream Products: 5-Benzyloxyindole, 5-Methoxyindole, (4-Benzyloxyphenyl)hydrazine; Downstream Products: 5-HYDROXY-DL-TRYPTOPHAN ETHYL ESTER HYDROCHLORIDE, 5-Hydroxy-1H-indole-3-carbaldehyde, 1H-Indol-5-ol, 3-(1-methyl-4-piperidinyl)-.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "5-Hydroxyindole (CAS 1953-54-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-34685-0 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.