Epothilone D
Also known as: Epothilone D, 13-Desoxyepothilone B, Desoxyepothilone B, KOS-862, 4,8-Dihydroxy-5,5,7,9,13-pentamethyl-16-(1-methyl-2-(2-methyl-4-thiazolyl)ethenyl)-oxacyclohexadec-13-ene-2,6-dione
Epothilone D (CAS 189453-10-9) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C27H41NO5S and a molecular weight of 491.68 g/mol. Key properties include a melting point of 63-66°C, a boiling point of 657.7±55.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 351.6±31.5 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 189453-10-9
- Jingsj CID
- J-1097939-2
- Molecular Formula
- C27H41NO5S
- Molecular Weight
- 491.68 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 63-66°C |
|---|---|
| Boiling Point | 657.7±55.0 °C at 760 mmHg |
| Density | 1.1±0.1 g/cm3 |
| Flash Point | 351.6±31.5 °C |
| PSA | 124.96000 |
| LogP | 3.69 |
| Vapor Pressure | 0.0±2.1 mmHg at 25°C |
| Refractive Index | 1.526 |
| Storage Conditions | -20℃ |
Activity & Biological Data
| Target | Microtubule/Tubulin[1] |
|---|---|
| Additional Information | [1]. Konner J, et al. Phase I clinical, pharmacokinetic, and pharmacodynamic study of KOS-862 (Epothilone D) in patients with advanced solid tumors and lymphoma. Invest New Drugs. 2012 Dec;30(6):2294-302. [2]. Brunden KR, et al. Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy. J Neurosci. 2010 Oct 13;30(41):13861-6. |
Frequently Asked Questions
What is the CAS number of Epothilone D?
The CAS number of Epothilone D is 189453-10-9.
What are the molecular formula and molecular weight of Epothilone D?
Epothilone D has molecular formula C27H41NO5S and molecular weight 491.68 g/mol.
What are the upstream and downstream products of Epothilone D?
For Epothilone D, Downstream Products: Epothilone B.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Epothilone D (CAS 189453-10-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1097939-2 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.