(-)-Epigallocatechin gallate

(-)-表没食子儿茶素没食子酸酯

Also known as: EGCG, Epigallocatechin 3-gallate, (-)-Epigallocatechin 3-O-gallate, Teavigo, (-)-cis-3,3',4',5,5',7-Hexahydroxy-flavane-3-gallate

(-)-Epigallocatechin gallate (CAS 989-51-5) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C22H18O11 and a molecular weight of 458.372 g/mol. It is also known as EGCG, Epigallocatechin 3-gallate and (-)-Epigallocatechin 3-O-gallate. Key properties include a melting point of 222-224°C, a boiling point of 909.1±65.0 °C at 760 mmHg, a density of 1.9±0.1 g/cm3 and a flash point of 320.0±27.8 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 989-51-5
Jingsj CID: J-26487-7
Molecular Formula: C₂₂H₁₈O₁₁
Chinese Name: (-)-表没食子儿茶素没食子酸酯
Molecular Weight: 458.372 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	222-224°C
Boiling Point	909.1±65.0 °C at 760 mmHg
Density	1.9±0.1 g/cm3
Flash Point	320.0±27.8 °C
Exact Mass	458.084900
PSA	197.37000
LogP	2.08
Vapor Pressure	0.0±0.3 mmHg at 25°C
Refractive Index	1.857

Activity & Biological Data

Target	EGFR HER2 HER3
Additional Information	[1]. De Amicis F, et al. Epigallocatechin gallate inhibits growth and Epithelial-to-Mesenchymal Transition in human thyroid carcinoma cell lines. J Cell Physiol. 2013 Apr 1. [2]. Jin H, et al. Epigallocatechin gallate inhibits the proliferation of colorectal cancer cells by regulating Notch signaling. Onco Targets Ther. 2013;6:145-53. [3]. Wing Pui Tsang, et al. Epigallocatechin gallate up-regulation of miR-16 and induction of apoptosis in human cancer cells. The Journal of Nutritional Biochemistry. 2010, 21(2): 140-146.

Target

EGFR HER2 HER3

Additional Information

[1]. De Amicis F, et al. Epigallocatechin gallate inhibits growth and Epithelial-to-Mesenchymal Transition in human thyroid carcinoma cell lines. J Cell Physiol. 2013 Apr 1. [2]. Jin H, et al. Epigallocatechin gallate inhibits the proliferation of colorectal cancer cells by regulating Notch signaling. Onco Targets Ther. 2013;6:145-53. [3]. Wing Pui Tsang, et al. Epigallocatechin gallate up-regulation of miR-16 and induction of apoptosis in human cancer cells. The Journal of Nutritional Biochemistry. 2010, 21(2): 140-146.

Frequently Asked Questions

What is the CAS number of (-)-Epigallocatechin gallate?

The CAS number of (-)-Epigallocatechin gallate is 989-51-5.

What are the molecular formula and molecular weight of (-)-Epigallocatechin gallate?

(-)-Epigallocatechin gallate has molecular formula C22H18O11 and molecular weight 458.372 g/mol.

What are the upstream and downstream products of (-)-Epigallocatechin gallate?

For (-)-Epigallocatechin gallate, Upstream Products: 3,4,5-Tris(benzyloxy)benzoic acid; Downstream Products: 1,1-diphenyl-2-picrylhydrazine, Gallic acid, (-)-Epigallocatechin gallate.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "(-)-Epigallocatechin gallate (CAS 989-51-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-26487-7 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.