Fotemustine
福莫司汀
Also known as: 1-(2-chloroethyl)-3-(1-diethoxyphosphorylethyl)-1-nitrosourea, Diethyl (1-(3-(2-chloroethyl)-3-nitrosoureido)ethyl)phosphonate, Diethyl (1-{[(2-chloroethyl)(nitroso)carbamoyl]amino}ethyl)phosphonate, Fotemustin, Muphoran, S-10036, Phosphonic acid, P-[1-[[[(2-chloroethyl)nitrosoamino]carbonyl]amino]ethyl]-, diethyl ester, [1-[[[(2-Chloroethyl)nitrosoamino]carbonyl]amino]ethyl]phosphonic acid diethyl ester, MFCD00866278
Fotemustine (CAS 92118-27-9) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C9H19ClN3O5P and a molecular weight of 315.691 g/mol. It is also known as 1-(2-chloroethyl)-3-(1-diethoxyphosphorylethyl)-1-nitrosourea, Diethyl (1-(3-(2-chloroethyl)-3-nitrosoureido)ethyl)phosphonate and Diethyl (1-{[(2-chloroethyl)(nitroso)carbamoyl]amino}ethyl)phosphonate. Key properties include a melting point of 85ºC, a boiling point of 188 °C(lit.), a density of 1.4±0.1 g/cm3 and a flash point of 104 °F. It is classified under GHS with signal word Warning and hazard statements H351 — Suspected of causing cancer. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 92118-27-9
- Jingsj CID
- J-24706-9
- Molecular Formula
- C9H19ClN3O5P
- Chinese Name
- 福莫司汀
- Molecular Weight
- 315.691 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 85ºC |
|---|---|
| Boiling Point | 188 °C(lit.) |
| Density | 1.4±0.1 g/cm3 |
| Flash Point | 104 °F |
| Exact Mass | 315.075073 |
| PSA | 107.11000 |
| LogP | 1.26 |
| Refractive Index | 1.524 |
| Storage Conditions | 2-8°C |
GHS Safety & Compliance
- H351 — Suspected of causing cancer
Activity & Biological Data
| Target | DNA Alkylator[1] |
|---|---|
| Additional Information | [1]. Brakenhoff JP, et al. Molecular mechanisms of toxic effects of fotemustine in rat hepatocytes and subcellular rat liver fractions. Carcinogenesis. 1996 Apr;17(4):715-24. [2]. Merlin JL, et al. Enhancement of fotemustine (Muphoran) cytotoxicity by amifostine in malignant melanoma cell lines. Anticancer Drugs. 2002 Feb;13(2):141-7. |
Frequently Asked Questions
What is the CAS number of Fotemustine?
The CAS number of Fotemustine is 92118-27-9.
What are the molecular formula and molecular weight of Fotemustine?
Fotemustine has molecular formula C9H19ClN3O5P and molecular weight 315.691 g/mol.
Is Fotemustine hazardous?
Fotemustine has GHS signal word Warning and hazard statements H351 — Suspected of causing cancer.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Fotemustine (CAS 92118-27-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-24706-9 (accessed 2026-10-28).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.