Phenidone

Also known as: 1-Phenyl-3-pyrazolidinone, 1-Phenyl-3-pyrazolidone, 1-Phenyl-3-oxopyrazolidine, 1-Phenylpyrazolidin-3-one, Graphidone, Fenidon, Edaravone Impurity 16

Phenidone (CAS 92-43-3) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C9H10N2O and a molecular weight of 162.189 g/mol. Key properties include a melting point of 119-121 °C(lit.), a boiling point of 304.1±25.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 137.7±23.2 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed and H411 — Toxic to aquatic life with long lasting effects. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 92-43-3
Jingsj CID: J-36018-9
Molecular Formula: C₉H₁₀N₂O
Molecular Weight: 162.189 g/mol
Category: Ketones
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	119-121 °C(lit.)
Boiling Point	304.1±25.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	137.7±23.2 °C
Exact Mass	162.079315
PSA	32.34000
LogP	0.20
Vapor Pressure	0.0±0.7 mmHg at 25°C
Refractive Index	1.620
Stability	Stable, but light sensitive. Incompatible with strong acids, strong oxidizing agents, strong bases.
Additional Property	SOLUBLE IN HOT WATER

GHS Safety & Compliance

Irritant / Environmental HazardSignal word: Warning

H302 — Harmful if swallowed
H411 — Toxic to aquatic life with long lasting effects

Activity & Biological Data

Target	COX LOX
Additional Information	[1]. Moon C, et al. Phenidone, a dual inhibitor of cyclooxygenases and lipoxygenases, ameliorates rat paralysis in experimental autoimmune encephalomyelitis by suppressing its target enzymes. Brain Res. 2005;1035(2):206-210. [2]. Stern N, et al. The lipoxygenase inhibitor phenidone is a potent hypotensive agent in the spontaneously hypertensive rat. Am J Hypertens. 1993;6(1):52-58. [3]. Petrakiev A, et al. Emission spectral analysis using photographic plates treated with a phenidone developer. Talanta. 1969;16(12):1583-1587.

Target

COX LOX

Additional Information

[1]. Moon C, et al. Phenidone, a dual inhibitor of cyclooxygenases and lipoxygenases, ameliorates rat paralysis in experimental autoimmune encephalomyelitis by suppressing its target enzymes. Brain Res. 2005;1035(2):206-210. [2]. Stern N, et al. The lipoxygenase inhibitor phenidone is a potent hypotensive agent in the spontaneously hypertensive rat. Am J Hypertens. 1993;6(1):52-58. [3]. Petrakiev A, et al. Emission spectral analysis using photographic plates treated with a phenidone developer. Talanta. 1969;16(12):1583-1587.

Customs & Trade Information

HS Code	2933199090
Summary	2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Phenidone?

The CAS number of Phenidone is 92-43-3.

What are the molecular formula and molecular weight of Phenidone?

Phenidone has molecular formula C9H10N2O and molecular weight 162.189 g/mol.

Is Phenidone hazardous?

Phenidone has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H411 — Toxic to aquatic life with long lasting effects.

What are the upstream and downstream products of Phenidone?

For Phenidone, Upstream Products: Ethyl acrylate, Phenylhydrazine, 3-Amino-4,5-dihydro-1-phenylpyrazole; Downstream Products: 2-Phenyl-4-phenylacetamido-3-pyrazolin-5-one.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Phenidone (CAS 92-43-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-36018-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.