(4S)-N-Crotonyl-4-benzyl-2-oxazolidinone

Also known as: Locostatin, UIC-1005, (S)-(+)-4-Benzyl-3-crotonyl-2-oxazolidinone, (4S)-3-[(E)-but-2-enoyl]-4-benzyl-2-oxazolidinone, (S,E)-4-benzyl-3-(but-2-enoyl)oxazolidin-2-one, (N-Crotonyl)-(4S)-benzyl-2-oxazolidinone, (R)-4-benzyl-3-crotonyl-2-oxazolidinone, MFCD00278769

(4S)-N-Crotonyl-4-benzyl-2-oxazolidinone (CAS 90719-30-5) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C14H15NO3 and a molecular weight of 245.27800 g/mol. Key properties include a melting point of 84-88ºC(lit.), a boiling point of 351ºC at 760 mmHg, a density of 1.205 g/cm3 and a flash point of 166.1ºC. No supplier offers are currently listed; request a quote. Record last updated Nov 2, 2026.

CAS No.: 90719-30-5
Jingsj CID: J-5851-9
Molecular Formula: C₁₄H₁₅NO₃
Molecular Weight: 245.27800 g/mol
Category: Ketones
Last updated: 11/2/2026

Request MSDS / TDS

No offers for this compound yet.

Request a quote

Physicochemical Properties

Melting Point	84-88ºC(lit.)
Boiling Point	351ºC at 760 mmHg
Density	1.205 g/cm3
Flash Point	166.1ºC
Exact Mass	197.10500
PSA	46.61000
LogP	1.29870
Appearance	white to off-white
Additional Property	DMSO: ≥30mg/mL

Activity & Biological Data

Target	RKIP[3]
Additional Information	[1]. Beshir AB, et al. Locostatin Disrupts Association of Raf Kinase Inhibitor Protein With Binding Proteins by Modifying a Conserved Histidine Residue in the Ligand-Binding Pocket. For Immunopathol Dis Therap. 2011;2(1):47-58. [2]. Mc Henry KT, et al. A non-antibacterial oxazolidinone derivative that inhibits epithelial cell sheet migration. Chembiochem. 2002 Nov 4;3(11):1105-11. [3]. Lin X, et al. Inhibition of RKIP aggravates thioacetamide-induced acute liver failure in mice. Exp Ther Med. 2018 Oct;16(4):2992-2998.

Target

RKIP[3]

Additional Information

[1]. Beshir AB, et al. Locostatin Disrupts Association of Raf Kinase Inhibitor Protein With Binding Proteins by Modifying a Conserved Histidine Residue in the Ligand-Binding Pocket. For Immunopathol Dis Therap. 2011;2(1):47-58. [2]. Mc Henry KT, et al. A non-antibacterial oxazolidinone derivative that inhibits epithelial cell sheet migration. Chembiochem. 2002 Nov 4;3(11):1105-11. [3]. Lin X, et al. Inhibition of RKIP aggravates thioacetamide-induced acute liver failure in mice. Exp Ther Med. 2018 Oct;16(4):2992-2998.

Frequently Asked Questions

What is the CAS number of (4S)-N-Crotonyl-4-benzyl-2-oxazolidinone?

The CAS number of (4S)-N-Crotonyl-4-benzyl-2-oxazolidinone is 90719-30-5.

What are the molecular formula and molecular weight of (4S)-N-Crotonyl-4-benzyl-2-oxazolidinone?

(4S)-N-Crotonyl-4-benzyl-2-oxazolidinone has molecular formula C14H15NO3 and molecular weight 245.27800 g/mol.

What are the upstream and downstream products of (4S)-N-Crotonyl-4-benzyl-2-oxazolidinone?

For (4S)-N-Crotonyl-4-benzyl-2-oxazolidinone, Upstream Products: (E)-2-Butenoyl chloride, (S)-4-Benzyl-2-oxazolidinone, Crotonoyl chloride; Downstream Products: (R)-3-(3-Methylbutanoyl)-4-benzyloxazolidin-2-one, (3S,4S)-4-Benzyl-3-(3-methylpentanoyl)oxazolidin-2-one.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 11/2/2026

How to cite: Jingsj. "(4S)-N-Crotonyl-4-benzyl-2-oxazolidinone (CAS 90719-30-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-5851-9 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.