Hypromellose

羟丙基甲基纤维素

Also known as: Hydroxypropyl methyl cellulose, HPMC, MHPC, Hydroxypropyl methylcellulose, Methyl cellulose hydroxypropyl ether, E464

Hypromellose (CAS 9004-65-3) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C18H38O14 and a molecular weight of 478.49 g/mol. It is also known as Hydroxypropyl methyl cellulose, HPMC and MHPC. Key property: a density of 1.39. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 9004-65-3
Jingsj CID: J-1992827-8
Molecular Formula: C₁₈H₃₈O₁₄
Chinese Name: 羟丙基甲基纤维素
Molecular Weight: 478.49 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Density	1.39
Appearance	powder
Additional Property	H2O: 50 mg/mL, clear to very faintly turbid, faintly yellow \| SOLUBLE

Activity & Biological Data

Additional Information	[1]. Li CL, et al. The use of hypromellose in oral drug delivery. J Pharm Pharmacol. 2005 May;57(5):533-46. [2]. Braund R, et al. Hypromellose films for the delivery of growth factors for wound healing. [3]. Capita L, et al. Prospective evaluation of hypromellose 2% for punctal occlusion in patients with dry eye. Cornea. 2015 Feb;34(2):188-92. [4]. Ban SJ, et al. Antihyperglycemic and antioxidative effects of Hydroxyethyl Methylcellulose (HEMC) and Hydroxypropyl Methylcellulose (HPMC) in mice fed with a high fat diet. Int J Mol Sci. 2012;13(3):3738-50.

Additional Information

[1]. Li CL, et al. The use of hypromellose in oral drug delivery. J Pharm Pharmacol. 2005 May;57(5):533-46. [2]. Braund R, et al. Hypromellose films for the delivery of growth factors for wound healing. [3]. Capita L, et al. Prospective evaluation of hypromellose 2% for punctal occlusion in patients with dry eye. Cornea. 2015 Feb;34(2):188-92. [4]. Ban SJ, et al. Antihyperglycemic and antioxidative effects of Hydroxyethyl Methylcellulose (HEMC) and Hydroxypropyl Methylcellulose (HPMC) in mice fed with a high fat diet. Int J Mol Sci. 2012;13(3):3738-50.

Frequently Asked Questions

What is the CAS number of Hypromellose?

The CAS number of Hypromellose is 9004-65-3.

What are the molecular formula and molecular weight of Hypromellose?

Hypromellose has molecular formula C18H38O14 and molecular weight 478.49 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Hypromellose (CAS 9004-65-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1992827-8 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.