Thiolutin

硫藤黄素

Also known as: Acetopyrrothine, Acetopyrrothin, N-(4-Methyl-5-oxo-4,5-dihydro-[1,2]dithiolo[4,3-b]pyrrol-6-yl)acetamide, 6-Acetamido-4-methyl-1,2-dithiolo[4,3-b]pyrrol-5(4H)-one, 6-(Acetylamino)-4-methyl-1,2-dithiolo(4,3-b)pyrrol-5(4H)-one, N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)acetamide, 3-Acetamido-5-methylpyrrolin-4-one[4,3-d]-1,2-dithiole, MFCD07370147, NSC 3927

Thiolutin (CAS 87-11-6) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C8H8N2O2S2 and a molecular weight of 228.291 g/mol. It is also known as Acetopyrrothine, Acetopyrrothin and N-(4-Methyl-5-oxo-4,5-dihydro-[1,2]dithiolo[4,3-b]pyrrol-6-yl)acetamide. Key properties include a melting point of 273-276℃, a boiling point of 478.6±45.0 °C at 760 mmHg, a density of 1.6±0.1 g/cm3 and a flash point of 243.3±28.7 °C. It is classified under GHS with signal word Danger and hazard statements H300. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
87-11-6
Jingsj CID
J-1345263-4
Molecular Formula
C8H8N2O2S2
Chinese Name
硫藤黄素
Molecular Weight
228.291 g/mol
Category
Organic Compounds
Last updated
8/21/2026

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Physicochemical Properties

Melting Point273-276℃
Boiling Point478.6±45.0 °C at 760 mmHg
Density1.6±0.1 g/cm3
Flash Point243.3±28.7 °C
Exact Mass228.002716
PSA107.58000
LogP0.99
Vapor Pressure0.0±1.2 mmHg at 25°C
Refractive Index1.721
Additional PropertyDMSO: 5 mg/mL

GHS Safety & Compliance

Acute ToxicitySignal word: Danger
  • H300

Activity & Biological Data

Additional Information[1]. Lauinger L, et al. Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases. Nat Chem Biol. 2017 Jul;13(7):709-714. [2]. Jia Y, et al. Thiolutin inhibits endothelial cell adhesion by perturbing Hsp27 interactions with components of the actin and intermediate filament cytoskeleton. Cell Stress Chaperones. 2010 Mar;15(2):165-81.

Customs & Trade Information

HS Code2933990090
Summary2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Thiolutin?

The CAS number of Thiolutin is 87-11-6.

What are the molecular formula and molecular weight of Thiolutin?

Thiolutin has molecular formula C8H8N2O2S2 and molecular weight 228.291 g/mol.

Is Thiolutin hazardous?

Thiolutin has GHS signal word Danger and hazard statements H300.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Thiolutin (CAS 87-11-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1345263-4 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.