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Pheniramine

Also known as: Trimeton, Prophenpyridamine, Avil, Histapyridamine, Propheniramine, Feniramine, Pyriton, Tripoton, Metron, N,N-dimethyl-3-phenyl-3-pyridin-2-ylpropan-1-amine, Dexchlorpheniramine EP Impurity A

Pheniramine (CAS 86-21-5) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C16H20N2 and a molecular weight of 240.34300 g/mol. Key properties include a melting point of 30-34 °C(lit.), a boiling point of 84 °C20 mm Hg(lit.), a density of 1.018 g/cm3 and a flash point of 81.7 °C. It is classified under GHS with signal word Danger and hazard statements H225 — Highly flammable liquid and vapour, H301 — Toxic if swallowed and H311 — Toxic in contact with skin. No supplier offers are currently listed; request a quote. Record last updated Nov 2, 2026.

CAS No.
86-21-5
Jingsj CID
J-34009-0
Molecular Formula
C16H20N2
Molecular Weight
240.34300 g/mol
Category
Organic Compounds
Last updated
11/2/2026

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Physicochemical Properties

Melting Point30-34 °C(lit.)
Boiling Point84 °C20 mm Hg(lit.)
Density1.018 g/cm3
Flash Point81.7 °C
Exact Mass240.16300
PSA16.13000
LogP3.16520
Refractive Index1.556
Storage Conditions?20°C

GHS Safety & Compliance

Flammable / Acute Toxicity / Health HazardSignal word: Danger
  • H225 — Highly flammable liquid and vapour
  • H301 — Toxic if swallowed
  • H311 — Toxic in contact with skin
  • H331 — Toxic if inhaled
  • H370 — Causes damage to organs

Activity & Biological Data

TargetH1 Receptor:1.01 mM (IC50)
Additional Information[1]. Sharma A, et al. Classic histamine H1 receptor antagonists: a critical review of their metabolic and pharmacokinetic fate from a bird's eye view. Curr Drug Metab. 2003 Apr;4(2):105-29. [2]. Brown RD, et al. Alpha 1-adrenergic and H1-histamine receptor control of intracellular Ca2+ in a muscle cell line: the influence of prior agonist exposure on receptor responsiveness. Mol Pharmacol. 1986 Jun;29(6):531-9. [3]. Jangi SM, et al. Apoptosis of human T-cell acute lymphoblastic leukemia cells by diphenhydramine, an H1 histamine receptor antagonist. Oncol Res. 2004;14(7-8):363-72. [4]. Hung CH, et al. Spinal anesthesia with diphenhydramine and pheniramine in rats. Eur J Pharmacol. 2011 Dec 30;673(1-3):20-4.

Customs & Trade Information

HS Code2933399090
Summary2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Pheniramine?

The CAS number of Pheniramine is 86-21-5.

What are the molecular formula and molecular weight of Pheniramine?

Pheniramine has molecular formula C16H20N2 and molecular weight 240.34300 g/mol.

Is Pheniramine hazardous?

Pheniramine has GHS signal word Danger and hazard statements H225 — Highly flammable liquid and vapour; H301 — Toxic if swallowed; H311 — Toxic in contact with skin.

What are the upstream and downstream products of Pheniramine?

For Pheniramine, Upstream Products: Dimethylamine, Acetylene.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Pheniramine (CAS 86-21-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-34009-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.