Zofenopril calcium

佐芬普利钙

Also known as: Zofenopril calcium salt, (4S)-1-[(2S)-3-(benzoylthio)-2-methyl-1-oxopropyl]-4-(phenylthio)-L-proline calcium salt, Calcium bis[(2S,4S)-1-[(2S)-3-(benzoylsulfanyl)-2-methylpropanoyl]-4-(phenylsulfanyl)-2-pyrrolidinecarboxylate], Calcium bis[(2S,4S)-1-[(2S)-3-(benzoylsulfanyl)-2-methylpropanoyl]-4-(phenylsulfanyl)pyrrolidine-2-carboxylate], L-Proline, 1-[(2S)-3-(benzoylthio)-2-methyl-1-oxopropyl]-4-(phenylthio)-, calcium salt, (4S)- (2:1), SQ26991, ZOPRACE, MFCD08704648

Zofenopril calcium (CAS 81938-43-4) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C22H22Ca0.5NO4S2 and a molecular weight of 448.58 g/mol. It is also known as Zofenopril calcium salt, (4S)-1-[(2S)-3-(benzoylthio)-2-methyl-1-oxopropyl]-4-(phenylthio)-L-proline calcium salt and Calcium bis[(2S,4S)-1-[(2S)-3-(benzoylsulfanyl)-2-methylpropanoyl]-4-(phenylsulfanyl)-2-pyrrolidinecarboxylate]. Key properties include a melting point of >250ºC, a boiling point of 646.3ºC at 760 mmHg, a density of 1.34 g/cm3 and a flash point of 344.7ºC. It is classified under GHS with signal word Warning and hazard statements H410 — Very toxic to aquatic life with long lasting effects. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 81938-43-4
Jingsj CID: J-1958013-7
Molecular Formula: C₂₂H₂₂Ca₀₅NO₄S₂
Chinese Name: 佐芬普利钙
Molecular Weight: 448.58 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	>250ºC
Boiling Point	646.3ºC at 760 mmHg
Density	1.34 g/cm3
Flash Point	344.7ºC
PSA	228.56000
LogP	7.80660
Storage Conditions	Refrigerator

GHS Safety & Compliance

Environmental HazardSignal word: Warning

H410 — Very toxic to aquatic life with long lasting effects

Activity & Biological Data

Additional Information	[1]. Dal Bo, L., P. Mazzucchelli, and A. Marzo, Assay of zofenopril and its active metabolite zofenoprilat by liquid chromatography coupled with tandem mass spectrometry. J Chromatogr B Biomed Sci Appl, 2000. 749(2): p. 287-94. [2]. Kalender, A.M., et al., Effect of Zofenopril on regeneration of sciatic nerve crush injury in a rat model. J Brachial Plex Peripher Nerve Inj, 2009. 4: p. 6. [3]. Frascarelli, S., et al., Effects of zofenopril on cardiac sarcoplasmic reticulum calcium handling. J Cardiovasc Pharmacol, 2009. 54(5): p. 456-63.

Additional Information

[1]. Dal Bo, L., P. Mazzucchelli, and A. Marzo, Assay of zofenopril and its active metabolite zofenoprilat by liquid chromatography coupled with tandem mass spectrometry. J Chromatogr B Biomed Sci Appl, 2000. 749(2): p. 287-94. [2]. Kalender, A.M., et al., Effect of Zofenopril on regeneration of sciatic nerve crush injury in a rat model. J Brachial Plex Peripher Nerve Inj, 2009. 4: p. 6. [3]. Frascarelli, S., et al., Effects of zofenopril on cardiac sarcoplasmic reticulum calcium handling. J Cardiovasc Pharmacol, 2009. 54(5): p. 456-63.

Frequently Asked Questions

What is the CAS number of Zofenopril calcium?

The CAS number of Zofenopril calcium is 81938-43-4.

What are the molecular formula and molecular weight of Zofenopril calcium?

Zofenopril calcium has molecular formula C22H22Ca0.5NO4S2 and molecular weight 448.58 g/mol.

Is Zofenopril calcium hazardous?

Zofenopril calcium has GHS signal word Warning and hazard statements H410 — Very toxic to aquatic life with long lasting effects.

What are the upstream and downstream products of Zofenopril calcium?

For Zofenopril calcium, Upstream Products: Zofenopril.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Zofenopril calcium (CAS 81938-43-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1958013-7 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.