Musk ketone

Also known as: Ketone musk, Ketone Moschus, 1-(4-tert-Butyl-2,6-dimethyl-3,5-dinitrophenyl)ethanone, 1-[4-(1,1-Dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl]ethanone, 4'-tert-Butyl-2',6'-dimethyl-3',5'-dinitroacetophenone, 2-Acetyl-5-tert-butyl-4,6-dinitroxylene, 1-Acetyl-4-tert-butyl-2,6-dimethyl-3,5-dinitrobenzene, 3,5-Dinitro-2,6-dimethyl-4-tert-butylacetophenone

Musk ketone (CAS 81-14-1) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C14H18N2O5 and a molecular weight of 294.30 g/mol. Key properties include a melting point of 135-139 °C(lit.), a boiling point of 369.0±42.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 153.2±20.7 °C. It is classified under GHS with signal word Warning and hazard statements H351 — Suspected of causing cancer and H410 — Very toxic to aquatic life with long lasting effects. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 81-14-1
Jingsj CID: J-798833-2
Molecular Formula: C₁₄H₁₈N₂O₅
Molecular Weight: 294.30 g/mol
Category: Ketones
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	135-139 °C(lit.)
Boiling Point	369.0±42.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	153.2±20.7 °C
Exact Mass	294.121582
PSA	108.71000
LogP	3.86
Vapor Pressure	0.0±0.8 mmHg at 25°C
Refractive Index	1.548
Stability	Stable. Incompatible with strong oxidizing agents, strong acids, strong bases.
Additional Property	Insoluble (

GHS Safety & Compliance

Health Hazard / Environmental HazardSignal word: Warning

H351 — Suspected of causing cancer
H410 — Very toxic to aquatic life with long lasting effects

Activity & Biological Data

Additional Information	[1]. Yamagishi T, et al. Identification of musk xylene and musk ketone in freshwater fish collected from the Tama River, Tokyo. Bull Environ Contam Toxicol. 1981 May;26(5):656-62. [2]. Mersch-Sundermann V, et al. Musk ketone enhances benzo(a)pyrene induced mutagenicity in human derived Hep G2 cells. Mutat Res. 2001 Aug 22;495(1-2):89-96. [3]. Zhou Z, et al. Musk Ketone Induces Neural Stem Cell Proliferation and Differentiation in Cerebral Ischemia via Activation of the PI3K/Akt Signaling Pathway. Neuroscience. 2020 May 21;435:1-9.

Additional Information

[1]. Yamagishi T, et al. Identification of musk xylene and musk ketone in freshwater fish collected from the Tama River, Tokyo. Bull Environ Contam Toxicol. 1981 May;26(5):656-62. [2]. Mersch-Sundermann V, et al. Musk ketone enhances benzo(a)pyrene induced mutagenicity in human derived Hep G2 cells. Mutat Res. 2001 Aug 22;495(1-2):89-96. [3]. Zhou Z, et al. Musk Ketone Induces Neural Stem Cell Proliferation and Differentiation in Cerebral Ischemia via Activation of the PI3K/Akt Signaling Pathway. Neuroscience. 2020 May 21;435:1-9.

Frequently Asked Questions

What is the CAS number of Musk ketone?

The CAS number of Musk ketone is 81-14-1.

What are the molecular formula and molecular weight of Musk ketone?

Musk ketone has molecular formula C14H18N2O5 and molecular weight 294.30 g/mol.

Is Musk ketone hazardous?

Musk ketone has GHS signal word Warning and hazard statements H351 — Suspected of causing cancer; H410 — Very toxic to aquatic life with long lasting effects.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Musk ketone (CAS 81-14-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-798833-2 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.