D-AP4

D(-)-2-氨基-4-膦酰基丁酸

Also known as: D-AP4, D(-)-2-Amino-4-phosphonobutanoic acid, D(-)-2-Amino-4-phosphonobutyric acid, (2R)-2-Amino-4-phosphonobutanoic acid, (R)-2-Amino-4-phosphonobutanoic acid, D-2-Amino-4-phosphonobutanoic acid, D-2-Amino-4-phosphonobutyric acid

D-AP4 (CAS 78739-01-2) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C4H10NO5P and a molecular weight of 183.10000 g/mol. It is also known as D(-)-2-Amino-4-phosphonobutanoic acid, D(-)-2-Amino-4-phosphonobutyric acid and (2R)-2-Amino-4-phosphonobutanoic acid. Key properties include a melting point of 212-213ºC, a boiling point of 491.7ºC at 760 mmHg, a density of 1.628g/cm3 and a flash point of 251.2ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 78739-01-2
Jingsj CID: J-43817-3
Molecular Formula: C₄H₁₀NO₅P
Chinese Name: D(-)-2-氨基-4-膦酰基丁酸
Molecular Weight: 183.10000 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	212-213ºC
Boiling Point	491.7ºC at 760 mmHg
Density	1.628g/cm3
Flash Point	251.2ºC
Exact Mass	183.03000
PSA	130.66000
Refractive Index	1.545

Activity & Biological Data

Additional Information	[1]. Evans RH, et al. The effects of a series of omega-phosphonic alpha-carboxylic amino acids on electrically evoked and excitant amino acid-induced responses in isolated spinal cord preparations. Br J Pharmacol. 1982;75(1):65-75. [2]. Schulte MK, et al. Utilization of the resolved L-isomer of 2-amino-6-phosphonohexanoic acid (L-AP6) as a selective agonist for a quisqualate-sensitized site in hippocampal CA1 pyramidal neurons. Brain Res. 1994;649(1-2):203-207. [3]. Toms NJ, et al. Inhibition of AMPA receptor-stimulated 57Co2+ influx by D- and L-2-amino-4-phosphonobutanoic acid (D- and L-AP4) and L-serine-O-phosphate (L-SOP) in cultured cerebellar granule cells. Neuropharmacology. 1997;36(3):335-343.

Additional Information

[1]. Evans RH, et al. The effects of a series of omega-phosphonic alpha-carboxylic amino acids on electrically evoked and excitant amino acid-induced responses in isolated spinal cord preparations. Br J Pharmacol. 1982;75(1):65-75. [2]. Schulte MK, et al. Utilization of the resolved L-isomer of 2-amino-6-phosphonohexanoic acid (L-AP6) as a selective agonist for a quisqualate-sensitized site in hippocampal CA1 pyramidal neurons. Brain Res. 1994;649(1-2):203-207. [3]. Toms NJ, et al. Inhibition of AMPA receptor-stimulated 57Co2+ influx by D- and L-2-amino-4-phosphonobutanoic acid (D- and L-AP4) and L-serine-O-phosphate (L-SOP) in cultured cerebellar granule cells. Neuropharmacology. 1997;36(3):335-343.

Frequently Asked Questions

What is the CAS number of D-AP4?

The CAS number of D-AP4 is 78739-01-2.

What are the molecular formula and molecular weight of D-AP4?

D-AP4 has molecular formula C4H10NO5P and molecular weight 183.10000 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "D-AP4 (CAS 78739-01-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-43817-3 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.