SR 57227 hydrochloride
4-氨基-1-(6-氯-2-吡啶基)哌啶盐酸盐
Also known as: SR 57227A, SR 57227A hydrochloride, SR57227A, SR57227HCl, CM57227, 1-(6-chloropyridin-2-yl)piperidin-4-amine hydrochloride, 4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride, 1-(6-chloro-2-pyridinyl)-4-piperidinamine hydrochloride
SR 57227 hydrochloride (CAS 77145-61-0) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C10H15Cl2N3 and a molecular weight of 248.15200 g/mol. It is also known as SR 57227A, SR 57227A hydrochloride and SR57227A. Key properties include a boiling point of 367.6ºC at 760 mmHg and a flash point of 176.1ºC. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 77145-61-0
- Jingsj CID
- J-30986-6
- Molecular Formula
- C10H15Cl2N3
- Chinese Name
- 4-氨基-1-(6-氯-2-吡啶基)哌啶盐酸盐
- Molecular Weight
- 248.15200 g/mol
- Category
- Pharma Intermediates
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Boiling Point | 367.6ºC at 760 mmHg |
|---|---|
| Flash Point | 176.1ºC |
| Exact Mass | 247.06400 |
| PSA | 42.15000 |
| LogP | 3.22980 |
GHS Safety & Compliance
- H301 — Toxic if swallowed
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Additional Information | [1]. Poncelet M, et al, Le Fur G. Antidepressant-like effects of SR 57227A, a 5-HT3 receptor agonist, in rodents. J Neural Transm Gen Sect. 1995;102(2):83‐90. [2]. Bachy A, et al. SR 57227A: a potent and selective agonist at central and peripheral 5-HT3 receptors in vitro and in vivo. Eur J Pharmacol. 1993;237(2-3):299‐309. |
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Frequently Asked Questions
What is the CAS number of SR 57227 hydrochloride?
The CAS number of SR 57227 hydrochloride is 77145-61-0.
What are the molecular formula and molecular weight of SR 57227 hydrochloride?
SR 57227 hydrochloride has molecular formula C10H15Cl2N3 and molecular weight 248.15200 g/mol.
Is SR 57227 hydrochloride hazardous?
SR 57227 hydrochloride has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H315 — Causes skin irritation; H319 — Causes serious eye irritation.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "SR 57227 hydrochloride (CAS 77145-61-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-30986-6 (accessed 2026-10-28).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.