Tris(hydroxymethyl)aminomethane
Also known as: Trometamol, Tromethamine, TRIS, Trizma, THAM, Tris base, 2-Amino-2-(hydroxymethyl)-1,3-propanediol, Tris(hydroxymethyl)aminomethane, Pehanorm, Talatrol, Tham-E, riladyl, thamset, TRISMAT
Tris(hydroxymethyl)aminomethane (CAS 77-86-1) is a compound in the Aliphatic Hydrocarbons category listed in the Jingsj chemical database. It has the molecular formula C4H11NO3 and a molecular weight of 121.135 g/mol. Key properties include a melting point of 167-172 °C(lit.), a boiling point of 357.0±37.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 169.7±26.5 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 77-86-1
- Jingsj CID
- J-32676-4
- Molecular Formula
- C4H11NO3
- Molecular Weight
- 121.135 g/mol
- Category
- Aliphatic Hydrocarbons
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 167-172 °C(lit.) |
|---|---|
| Boiling Point | 357.0±37.0 °C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 169.7±26.5 °C |
| Exact Mass | 121.073891 |
| PSA | 86.71000 |
| LogP | -1.38 |
| Vapor Pressure | 0.0±1.8 mmHg at 25°C |
| Refractive Index | 1.544 |
| Additional Property | 550 g/L (25 ºC) |
Activity & Biological Data
| Additional Information | [1]. Nahas GG, et al. Guidelines for the treatment of acidaemia with THAM. Drugs. 1998 Feb;55(2):191-224. |
|---|
Customs & Trade Information
| HS Code | 2922199090 |
|---|---|
| Summary | 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of Tris(hydroxymethyl)aminomethane?
The CAS number of Tris(hydroxymethyl)aminomethane is 77-86-1.
What are the molecular formula and molecular weight of Tris(hydroxymethyl)aminomethane?
Tris(hydroxymethyl)aminomethane has molecular formula C4H11NO3 and molecular weight 121.135 g/mol.
What are the upstream and downstream products of Tris(hydroxymethyl)aminomethane?
For Tris(hydroxymethyl)aminomethane, Upstream Products: Acrylamide, Tris(hydroxymethyl)nitromethane; Downstream Products: tert-Butyl N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]carbamate, Nicotinic acid, Pentafluorobenzene.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Tris(hydroxymethyl)aminomethane (CAS 77-86-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-32676-4 (accessed 2026-11-07).
Data for reference only; verify product details with suppliers before purchase.