Methotrexate disodium salt

甲氨蝶呤二钠盐

Also known as: Methotrexate disodium, Disodium N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamate, disodium 2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)amino]pentanedioate, Amethopterin sodium salt, MTX disodium, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid disodium salt

Methotrexate disodium salt (CAS 7413-34-5) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C20H20N8Na2O5 and a molecular weight of 498.403 g/mol. It is also known as Methotrexate disodium, Disodium N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamate and disodium 2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)amino]pentanedioate. Key property: a boiling point of 823℃. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 7413-34-5
Jingsj CID: J-36948-0
Molecular Formula: C₂₀H₂₀N₈Na₂O₅
Chinese Name: 甲氨蝶呤二钠盐
Molecular Weight: 498.403 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	823℃
Exact Mass	498.135193
PSA	216.20000

Activity & Biological Data

Target	Traditional Cytotoxic Agents
Additional Information	[1]. Tian H, et al. Understanding the mechanisms of action of methotrexate: implications for the treatment of rheumatoid arthritis. Bull NYU Hosp Jt Dis. 2007;65(3):168-73. [2]. Swierkot J, et al. Methotrexate in rheumatoid arthritis. Pharmacol Rep. 2006 Jul-Aug;58(4):473-92. [3]. Swierkot J, et al. Methotrexate in rheumatoid arthritis. Pharmacol Rep. 2006 Jul-Aug;58(4):473-92. [4]. Banji D, et al. Evaluation of the concomitant use of methotrexate and curcumin on Freund's complete adjuvant-induced arthritis and hematological indices in rats. Indian J Pharmacol. 2011;43(5):546-550.

Target

Traditional Cytotoxic Agents

Additional Information

[1]. Tian H, et al. Understanding the mechanisms of action of methotrexate: implications for the treatment of rheumatoid arthritis. Bull NYU Hosp Jt Dis. 2007;65(3):168-73. [2]. Swierkot J, et al. Methotrexate in rheumatoid arthritis. Pharmacol Rep. 2006 Jul-Aug;58(4):473-92. [3]. Swierkot J, et al. Methotrexate in rheumatoid arthritis. Pharmacol Rep. 2006 Jul-Aug;58(4):473-92. [4]. Banji D, et al. Evaluation of the concomitant use of methotrexate and curcumin on Freund's complete adjuvant-induced arthritis and hematological indices in rats. Indian J Pharmacol. 2011;43(5):546-550.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Methotrexate disodium salt?

The CAS number of Methotrexate disodium salt is 7413-34-5.

What are the molecular formula and molecular weight of Methotrexate disodium salt?

Methotrexate disodium salt has molecular formula C20H20N8Na2O5 and molecular weight 498.403 g/mol.

What are the upstream and downstream products of Methotrexate disodium salt?

For Methotrexate disodium salt, Upstream Products: Methotrexate.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Methotrexate disodium salt (CAS 7413-34-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-36948-0 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.