Apraclonidine hydrochloride

盐酸安普乐定

Also known as: Apraclonidine HCl, ALO-2145, Iopidine hydrochloride, p-Aminoclonidine hydrochloride, 2-[(4-Amino-2,6-dichlorophenyl)imino]imidazolidine monohydrochloride, NC 14 hydrochloride

Apraclonidine hydrochloride (CAS 73218-79-8) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C9H11Cl3N4 and a molecular weight of 281.56900 g/mol. It is also known as Apraclonidine HCl, ALO-2145 and Iopidine hydrochloride. Key properties include a melting point of >230ºC, a boiling point of 395.5ºC at 760 mmHg, a density of 1.63 g/cm3 and a flash point of 193ºC. It is classified under GHS with signal word Danger and hazard statements H300 and H370 — Causes damage to organs. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
73218-79-8
Jingsj CID
J-1957201-5
Molecular Formula
C9H11Cl3N4
Chinese Name
盐酸安普乐定
Molecular Weight
281.56900 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point>230ºC
Boiling Point395.5ºC at 760 mmHg
Density1.63 g/cm3
Flash Point193ºC
Exact Mass280.00500
PSA62.44000
LogP3.16730
Storage Conditions2-8°C
StabilityMoisture Sensitive
Additional Property45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 1.4 mg/mL Solutions may be stored for several days at 4?#x00b0;C

GHS Safety & Compliance

Acute Toxicity / Health HazardSignal word: Danger
  • H300
  • H370 — Causes damage to organs

Activity & Biological Data

Additional Information[1]. Wijemanne S, et al. Apraclonidine in the treatment of ptosis. J Neurol Sci. 2017;376:129‐132. [2]. Searles RV, et al. Aqueous humor dynamics in anesthetized rats infused with intracameral apraclonidine. Pharmacology. 1999;58(4):220‐226.

Customs & Trade Information

HS Code2933290090
Summary2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Apraclonidine hydrochloride?

The CAS number of Apraclonidine hydrochloride is 73218-79-8.

What are the molecular formula and molecular weight of Apraclonidine hydrochloride?

Apraclonidine hydrochloride has molecular formula C9H11Cl3N4 and molecular weight 281.56900 g/mol.

Is Apraclonidine hydrochloride hazardous?

Apraclonidine hydrochloride has GHS signal word Danger and hazard statements H300; H370 — Causes damage to organs.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Apraclonidine hydrochloride (CAS 73218-79-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1957201-5 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.