6-(4-Fluorophenyl)-5-(pyridin-4-yl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole

6-(4-氟苯基)-5-(4-吡啶基)-2,3-二氢咪唑并[2,1-b]噻唑

Also known as: SKF 86002, 6-(4-Fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo[2,1-b]thiazole, 5-(4-Pyridyl)-6-(4-fluorophenyl)-2,3-dihydroimidazo[2,1-b]thiazole, Imidazo[2,1-b]thiazole, 6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)-, MFCD00869367

6-(4-Fluorophenyl)-5-(pyridin-4-yl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole (CAS 72873-74-6) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C16H12FN3S and a molecular weight of 297.350 g/mol. It is also known as SKF 86002, 6-(4-Fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo[2,1-b]thiazole and 5-(4-Pyridyl)-6-(4-fluorophenyl)-2,3-dihydroimidazo[2,1-b]thiazole. Key properties include a melting point of 189-190ºC(lit.), a boiling point of 476.1±55.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 241.7±31.5 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
72873-74-6
Jingsj CID
J-28069-5
Molecular Formula
C16H12FN3S
Chinese Name
6-(4-氟苯基)-5-(4-吡啶基)-2,3-二氢咪唑并[2,1-b]噻唑
Molecular Weight
297.350 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point189-190ºC(lit.)
Boiling Point476.1±55.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point241.7±31.5 °C
Exact Mass297.073608
PSA56.01000
LogP1.90
Vapor Pressure0.0±1.2 mmHg at 25°C
Refractive Index1.713

Activity & Biological Data

Additional Information[1]. Griswold DE, et al. SK&F 86002: a structurally novel anti-inflammatory agent that inhibits lipoxygenase- and cyclooxygenase-mediated metabolism of arachidonic acid. Biochem Pharmacol. 1987 Oct 15;36(20):3463-70. [2]. Frasch SC, et al. p38 mitogen-activated protein kinase-dependent and -independent intracellular signal transduction pathways leading to apoptosis in human neutrophils. J Biol Chem. 1998 Apr 3;273(14):8389-97. [3]. Nick JA, et al. Common and distinct intracellular signaling pathways in human neutrophils utilized by platelet activating factor and FMLP. J Clin Invest. 1997 Mar 1;99(5):975-86.

Customs & Trade Information

HS Code2934100090
Summary2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 6-(4-Fluorophenyl)-5-(pyridin-4-yl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole?

The CAS number of 6-(4-Fluorophenyl)-5-(pyridin-4-yl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole is 72873-74-6.

What are the molecular formula and molecular weight of 6-(4-Fluorophenyl)-5-(pyridin-4-yl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole?

6-(4-Fluorophenyl)-5-(pyridin-4-yl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole has molecular formula C16H12FN3S and molecular weight 297.350 g/mol.

What are the upstream and downstream products of 6-(4-Fluorophenyl)-5-(pyridin-4-yl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole?

For 6-(4-Fluorophenyl)-5-(pyridin-4-yl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole, Upstream Products: Pyridine, 1,2-Dibromoethane.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "6-(4-Fluorophenyl)-5-(pyridin-4-yl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole (CAS 72873-74-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-28069-5 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.