Pipemidic acid trihydrate

吡哌酸三水合物

Also known as: 8-Ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)pyrido[2,3-d]pyrimidine-6-carboxylic acid trihydrate, 8-Ethyl-5-oxo-2-(piperazin-1-yl)-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid trihydrate, Pipemidic acid hydrate, Pipemidic acid trihydrate CRS, Pipemidic acid trihydrate USP/EP/BP, Karunomazin

Pipemidic acid trihydrate (CAS 72571-82-5) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C14H17N5O3 and a molecular weight of 303.31600 g/mol. It is also known as 8-Ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)pyrido[2,3-d]pyrimidine-6-carboxylic acid trihydrate, 8-Ethyl-5-oxo-2-(piperazin-1-yl)-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid trihydrate and Pipemidic acid hydrate. Key properties include a melting point of 253-255°, a boiling point of 534.9ºC at 760 mmHg, a density of 1.41g/mLat 25°C (lit.) and a flash point of 277.3ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 72571-82-5
Jingsj CID: J-37509-4
Molecular Formula: C₁₄H₁₇N₅O₃
Chinese Name: 吡哌酸三水合物
Molecular Weight: 303.31600 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	253-255°
Boiling Point	534.9ºC at 760 mmHg
Density	1.41g/mLat 25°C (lit.)
Flash Point	277.3ºC
Exact Mass	303.13300
PSA	100.35000
LogP	0.31300
Storage Conditions	2-8°C
Additional Property	Very slightly soluble in water and in methylene chloride, practically insoluble in ethanol (96 per cent). It dissolves in dilute solutions of acids and of alkali hydroxides.

Activity & Biological Data

Additional Information	[1]. Iacovino R, et al. β-Cyclodextrin inclusion complex to improve physicochemical properties of pipemidic acid: characterization and bioactivity evaluation. Int J Mol Sci. 2013 Jun 25;14(7):13022-41. [2]. Aoyama H, et, al. Purification of Citrobacter freundii DNA gyrase and inhibition by quinolones. Antimicrob Agents Chemother. 1988 Jan;32(1):104-9. [3]. Shimizu M, et, al. Pipemidic acid: absorption, distribution, and excretion. Antimicrob Agents Chemother. 1975 Apr;7(4):441-6.

Additional Information

[1]. Iacovino R, et al. β-Cyclodextrin inclusion complex to improve physicochemical properties of pipemidic acid: characterization and bioactivity evaluation. Int J Mol Sci. 2013 Jun 25;14(7):13022-41. [2]. Aoyama H, et, al. Purification of Citrobacter freundii DNA gyrase and inhibition by quinolones. Antimicrob Agents Chemother. 1988 Jan;32(1):104-9. [3]. Shimizu M, et, al. Pipemidic acid: absorption, distribution, and excretion. Antimicrob Agents Chemother. 1975 Apr;7(4):441-6.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Pipemidic acid trihydrate?

The CAS number of Pipemidic acid trihydrate is 72571-82-5.

What are the molecular formula and molecular weight of Pipemidic acid trihydrate?

Pipemidic acid trihydrate has molecular formula C14H17N5O3 and molecular weight 303.31600 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Pipemidic acid trihydrate (CAS 72571-82-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-37509-4 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.