Rifabutin

利福布汀

Also known as: Ansamycin, Ansatipine, Mycobutin, LM-427, 4-N-Isobutylspiropiperidylrifamycin S, Antibiotic LM 427

Rifabutin (CAS 72559-06-9) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C46H62N4O11 and a molecular weight of 847.005 g/mol. It is also known as Ansamycin, Ansatipine and Mycobutin. Key properties include a melting point of 169-171ºC, a boiling point of 969.6±65.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 540.2±34.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
72559-06-9
Jingsj CID
J-1975813-4
Molecular Formula
C46H62N4O11
Chinese Name
利福布汀
Molecular Weight
847.005 g/mol
Category
Organic Compounds
Last updated
8/21/2026

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Physicochemical Properties

Melting Point169-171ºC
Boiling Point969.6±65.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point540.2±34.3 °C
Exact Mass846.441528
PSA205.55000
LogP3.45
Vapor Pressure0.0±0.3 mmHg at 25°C
Refractive Index1.623
Storage ConditionsAmber Vial, -20°C Freezer, Under Inert Atmosphere
Additional PropertyDMSO: >5mg/mL

Activity & Biological Data

TargetAntibacterial
Additional Information[1]. Review Article: Rifabutin in the Treatment of Refractory Helicobacter pylori Infection J. P. Gisbert, X. Calvet Issue Alimentary Pharmacology & Therapeutics Volume 35, Issue 2, pages 209-221, January 2012 [2]. Vourvahis M, Davis J, Wang R, Layton G, Choo HW, Chong CL, Tawadrous M.Effect of rifampin and rifabutin on the pharmacokinetics of lersivirine and effect of lersivirine on the pharmacokinetics of rifabutin and 25-o-desacetyl-rifabutin in healthy subjects.Antimicrob Agents Chemother. 2012 Aug;56(8):4303-9. [3]. Gisbert JP, Castro-Fernandez M, Perez-Aisa A, Cosme A, Molina-Infante J, Rodrigo L, Modolell I, Cabriada JL, Gisbert JL, Lamas E, Marcos E, Calvet X.Fourth-line rescue therapy with rifabutin in patients with three Helicobacter pylori eradication failures.Aliment Pharmacol Ther. 2012 Apr;35(8):941-7. doi: 10.1111/j.1365-2036.2012.05053.x. [4]. Gisbert JP, Calvet X.Review article: rifabutin in the treatment of refractory Helicobacter pylori infection.Aliment Pharmacol Ther. 2012 Jan;35(2):209-21. doi: 10.1111/j.1365-2036.2011.04937.x. [5]. Horne DJ, Spitters C, Narita M.Experience with rifabutin replacing rifampin in the treatment of tuberculosis.Int J Tuberc Lung Dis. 2011 Nov;15(11):1485-9, i.

Customs & Trade Information

HS Code2941903000

Frequently Asked Questions

What is the CAS number of Rifabutin?

The CAS number of Rifabutin is 72559-06-9.

What are the molecular formula and molecular weight of Rifabutin?

Rifabutin has molecular formula C46H62N4O11 and molecular weight 847.005 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Rifabutin (CAS 72559-06-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1975813-4 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.