Mitoxantrone hydrochloride
盐酸米托蒽醌
Also known as: Mitoxantrone dihydrochloride, Mitoxantrone HCl, Mitoxantrone 2HCl, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthraquinone dihydrochloride, 1,4-dihydroxy-5,8-bis({2-[(2-hydroxyethyl)amino]ethyl}amino)anthracene-9,10-dione dihydrochloride, Novantrone, NSC-310739, UNII-U6USW86RD0
Mitoxantrone hydrochloride (CAS 70476-82-3) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C22H30Cl2N4O6 and a molecular weight of 517.403 g/mol. It is also known as Mitoxantrone dihydrochloride, Mitoxantrone HCl and Mitoxantrone 2HCl. Key properties include a melting point of 203-205ºC, a boiling point of 805.7ºC at 760 mmHg and a flash point of 441.1ºC. It is classified under GHS with signal word Danger and hazard statements H340 and H360 — May damage fertility or the unborn child. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 70476-82-3
- Jingsj CID
- J-1961274-0
- Molecular Formula
- C22H30Cl2N4O6
- Chinese Name
- 盐酸米托蒽醌
- Molecular Weight
- 517.403 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 203-205ºC |
|---|---|
| Boiling Point | 805.7ºC at 760 mmHg |
| Flash Point | 441.1ºC |
| Exact Mass | 516.154236 |
| PSA | 163.18000 |
| LogP | 2.39260 |
GHS Safety & Compliance
- H340
- H360 — May damage fertility or the unborn child
Activity & Biological Data
| Target | PKC:8.5 μM (IC50) Topoisomerase II |
|---|---|
| Additional Information | [1]. Takeuchi N, et al. Inhibitory effect of mitoxantrone on activity of protein kinase C and growth of HL60 cells. J Biochem. 1992 Dec;112(6):762-7. [2]. Bellosillo B, et al. Mitoxantrone, a topoisomerase II inhibitor, induces apoptosis of B-chronic lymphocytic leukaemia cells. Br J Haematol. 1998 Jan;100(1):142-6. [3]. Venza I, et al. Class II-specific histone deacetylase inhibitors MC1568 and MC1575 suppress IL-8 expression in human melanoma cells. Pigment Cell Melanoma Res. 2013 Mar;26(2):193-204. [4]. Fujimoto S, et al. Antitumor activity of mitoxantrone against murine experimental tumors: comparative analysis against various antitumor antibiotics. Cancer Chemother Pharmacol. 1982;8(2):157-62. |
Customs & Trade Information
| HS Code | 2914610000 |
|---|---|
| Summary | 2914610000 anthracene-9,10-dione。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。Lowest tariff:5.5%。General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of Mitoxantrone hydrochloride?
The CAS number of Mitoxantrone hydrochloride is 70476-82-3.
What are the molecular formula and molecular weight of Mitoxantrone hydrochloride?
Mitoxantrone hydrochloride has molecular formula C22H30Cl2N4O6 and molecular weight 517.403 g/mol.
Is Mitoxantrone hydrochloride hazardous?
Mitoxantrone hydrochloride has GHS signal word Danger and hazard statements H340; H360 — May damage fertility or the unborn child.
What are the upstream and downstream products of Mitoxantrone hydrochloride?
For Mitoxantrone hydrochloride, Upstream Products: Disperse Blue 7, Ethanolamine.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Mitoxantrone hydrochloride (CAS 70476-82-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1961274-0 (accessed 2026-10-28).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.