Lornoxicam

Also known as: Chlortenoxicam, 6-Chloro-4-hydroxy-2-methyl-N-(2-pyridinyl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide, 6-Chloro-4-hydroxy-2-methyl-N-(2-pyridyl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide, 6-Chloro-4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide, 6-Chloro-4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-ylthieno[2,3-e]thiazine-3-carboxamide, Ro 13-9297, Xefo, Xefocam, Lorcam, AKOS 93662, CTX

Lornoxicam (CAS 70374-39-9) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C13H10ClN3O4S2 and a molecular weight of 371.819 g/mol. Key properties include a melting point of 225-230°C (dec.) and a density of 1.7±0.1 g/cm3. It is classified under GHS with signal word Danger and hazard statements H300. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 70374-39-9
Jingsj CID: J-37909-8
Molecular Formula: C₁₃H₁₀ClN₃O₄S₂
Molecular Weight: 371.819 g/mol
Category: Organohalogen Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	225-230°C (dec.)
Density	1.7±0.1 g/cm3
Exact Mass	370.980133
PSA	136.22000
LogP	2.18
Refractive Index	1.741
Storage Conditions	-20°C Freezer

GHS Safety & Compliance

Acute ToxicitySignal word: Danger

H300

Activity & Biological Data

Target	COX-1:5 nM (IC50, in cells) COX-2:45 nM (IC50, in cells)
Additional Information	[1]. Spyra S, et al. COX-2-selective inhibitors celecoxib and deracoxib modulate transient receptor potential vanilloid 3 channels. Br J Pharmacol. 2017 Aug;174(16):2696-2705. [2]. Rose, P. and C. Steinhauser, Comparison of Lornoxicam and Rofecoxib in Patients with Activated Osteoarthritis (COLOR Study). Clin Drug Investig, 2004. 24(4): p. 227-36. [3]. Bianchi, M. and A.E. Panerai, Effects of lornoxicam, piroxicam, and meloxicam in a model of thermal hindpaw hyperalgesia induced by formalin injection in rat tail. Pharmacol Res, 2002. 45(2): p. 101-5.

Target

COX-1:5 nM (IC50, in cells) COX-2:45 nM (IC50, in cells)

Additional Information

[1]. Spyra S, et al. COX-2-selective inhibitors celecoxib and deracoxib modulate transient receptor potential vanilloid 3 channels. Br J Pharmacol. 2017 Aug;174(16):2696-2705. [2]. Rose, P. and C. Steinhauser, Comparison of Lornoxicam and Rofecoxib in Patients with Activated Osteoarthritis (COLOR Study). Clin Drug Investig, 2004. 24(4): p. 227-36. [3]. Bianchi, M. and A.E. Panerai, Effects of lornoxicam, piroxicam, and meloxicam in a model of thermal hindpaw hyperalgesia induced by formalin injection in rat tail. Pharmacol Res, 2002. 45(2): p. 101-5.

Customs & Trade Information

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Lornoxicam?

The CAS number of Lornoxicam is 70374-39-9.

What are the molecular formula and molecular weight of Lornoxicam?

Lornoxicam has molecular formula C13H10ClN3O4S2 and molecular weight 371.819 g/mol.

Is Lornoxicam hazardous?

Lornoxicam has GHS signal word Danger and hazard statements H300.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Lornoxicam (CAS 70374-39-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-37909-8 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.