4,4'-(Hexafluoroisopropylidene)bis(p-phenyleneoxy)dianiline

2,2-双[4-(4-氨基苯氧基)苯基]六氟丙烷

Also known as: Benzenamine, 4,4'-[[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]bis(4,1-phenyleneoxy)]bis-, 2,2-Bis[4-(4-aminophenoxy)phenyl]hexafluoropropane, 4,4'-(Hexafluoroisopropylidene)bis(p-phenylenoxy)dianiline, HFBAPP, BAPOFP, BIS-AF-A, 1,1,1,3,3,3-Hexafluoro-2,2-bis[4-(4-aminophenoxy)phenyl]propane

4,4'-(Hexafluoroisopropylidene)bis(p-phenyleneoxy)dianiline (CAS 69563-88-8) is a compound in the Aromatic Hydrocarbons category listed in the Jingsj chemical database. It has the molecular formula C27H20F6N2O2 and a molecular weight of 518.450 g/mol. It is also known as Benzenamine, 4,4'-[[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]bis(4,1-phenyleneoxy)]bis-, 2,2-Bis[4-(4-aminophenoxy)phenyl]hexafluoropropane and 4,4'-(Hexafluoroisopropylidene)bis(p-phenylenoxy)dianiline. Key properties include a melting point of 159-163 °C(lit.), a boiling point of 544.8±50.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 283.3±30.1 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
69563-88-8
Jingsj CID
J-48649-1
Molecular Formula
C27H20F6N2O2
Chinese Name
2,2-双[4-(4-氨基苯氧基)苯基]六氟丙烷
Molecular Weight
518.450 g/mol
Category
Aromatic Hydrocarbons
Last updated
8/21/2026

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Physicochemical Properties

Melting Point159-163 °C(lit.)
Boiling Point544.8±50.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point283.3±30.1 °C
Exact Mass518.142883
PSA70.50000
LogP4.57
Vapor Pressure0.0±1.5 mmHg at 25°C
Refractive Index1.579

GHS Safety & Compliance

IrritantSignal word: Warning
  • H302 — Harmful if swallowed
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

Additional Information[1]. Loucif AJC, et al. GI-530159, a novel, selective, mechanosensitive two-pore-domain potassium (K2P ) channel opener, reduces rat dorsal root ganglion neuron excitability. Br J Pharmacol. 2018;175(12):2272-2283.

Customs & Trade Information

HS Code2922299090
Summary2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 4,4'-(Hexafluoroisopropylidene)bis(p-phenyleneoxy)dianiline?

The CAS number of 4,4'-(Hexafluoroisopropylidene)bis(p-phenyleneoxy)dianiline is 69563-88-8.

What are the molecular formula and molecular weight of 4,4'-(Hexafluoroisopropylidene)bis(p-phenyleneoxy)dianiline?

4,4'-(Hexafluoroisopropylidene)bis(p-phenyleneoxy)dianiline has molecular formula C27H20F6N2O2 and molecular weight 518.450 g/mol.

Is 4,4'-(Hexafluoroisopropylidene)bis(p-phenyleneoxy)dianiline hazardous?

4,4'-(Hexafluoroisopropylidene)bis(p-phenyleneoxy)dianiline has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H315 — Causes skin irritation; H319 — Causes serious eye irritation.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "4,4'-(Hexafluoroisopropylidene)bis(p-phenyleneoxy)dianiline (CAS 69563-88-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-48649-1 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.