Ginsenoside Rb3

人参皂苷Rb3

Also known as: Gypenoside IV, Ginsenoside Rb3 (SH), Ginsenoside Rb-3, Ginsenoside Rb 3, (3β,12β)-20-[(2-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 6-O-β-D-xylopyranosyl-β-D-glucopyranoside

Ginsenoside Rb3 (CAS 68406-26-8) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C53H90O22 and a molecular weight of 1079.269 g/mol. It is also known as Gypenoside IV, Ginsenoside Rb3 (SH) and Ginsenoside Rb-3. Key properties include a boiling point of 1117.1±65.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 629.4±34.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 68406-26-8
Jingsj CID: J-23132-1
Molecular Formula: C₅₃H₉₀O₂₂
Chinese Name: 人参皂苷Rb3
Molecular Weight: 1079.269 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	1117.1±65.0 °C at 760 mmHg
Density	1.4±0.1 g/cm3
Flash Point	629.4±34.3 °C
Exact Mass	1078.592407
PSA	357.06000
LogP	4.73
Vapor Pressure	0.0±0.6 mmHg at 25°C
Refractive Index	1.622
Storage Conditions	2-8°C

Activity & Biological Data

Target	NF-κB:8.2 μM (IC50, in 293T cell lines) COX-2 iNOS
Additional Information	[1]. He F, et al. Antitumor effects of dammarane-type saponins from steamed Notoginseng. Pharmacogn Mag. 2014 Jul;10(39):314-7. [2]. Zhu JR, et al. Protective effects of ginsenoside Rb(3) on oxygen and glucose deprivation-induced ischemic injury in PC12 cells. Acta Pharmacol Sin. 2010 Mar;31(3):273-80. [3]. Huang G, et al. Ginsenosides Rb3 and Rd reduce polyps formation while reinstate the dysbiotic gut microbiota and the intestinal microenvironment in Apc Min/+ mice. Sci Rep. 2017 Oct 2;7(1):12552.

Target

NF-κB:8.2 μM (IC50, in 293T cell lines) COX-2 iNOS

Additional Information

[1]. He F, et al. Antitumor effects of dammarane-type saponins from steamed Notoginseng. Pharmacogn Mag. 2014 Jul;10(39):314-7. [2]. Zhu JR, et al. Protective effects of ginsenoside Rb(3) on oxygen and glucose deprivation-induced ischemic injury in PC12 cells. Acta Pharmacol Sin. 2010 Mar;31(3):273-80. [3]. Huang G, et al. Ginsenosides Rb3 and Rd reduce polyps formation while reinstate the dysbiotic gut microbiota and the intestinal microenvironment in Apc Min/+ mice. Sci Rep. 2017 Oct 2;7(1):12552.

Frequently Asked Questions

What is the CAS number of Ginsenoside Rb3?

The CAS number of Ginsenoside Rb3 is 68406-26-8.

What are the molecular formula and molecular weight of Ginsenoside Rb3?

Ginsenoside Rb3 has molecular formula C53H90O22 and molecular weight 1079.269 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Ginsenoside Rb3 (CAS 68406-26-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-23132-1 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.