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Zonisamide

Also known as: AD-810, CI-912, Excegran, Excemide, Zonegran, ZON, 1,2-Benzisoxazole-3-methanesulfonamide, 3-Sulfamoylmethyl-1,2-benzisoxazole, 1-(1,2-Benzoxazol-3-yl)methanesulfonamide, MFCD00865316

Zonisamide (CAS 68291-97-4) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C8H8N2O3S and a molecular weight of 212.226 g/mol. Key properties include a melting point of 275°C dec., a boiling point of 457.2±47.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 230.3±29.3 °C. It is classified under GHS with signal word Danger and hazard statements H225 — Highly flammable liquid and vapour, H301 — Toxic if swallowed and H311 — Toxic in contact with skin. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
68291-97-4
Jingsj CID
J-19269-8
Molecular Formula
C8H8N2O3S
Molecular Weight
212.226 g/mol
Category
Organic Bases
Last updated
8/21/2026

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Physicochemical Properties

Melting Point275°C dec.
Boiling Point457.2±47.0 °C at 760 mmHg
Density1.5±0.1 g/cm3
Flash Point230.3±29.3 °C
Exact Mass212.025558
PSA94.57000
LogP-0.10
Vapor Pressure0.0±1.1 mmHg at 25°C
Refractive Index1.656
Additional PropertyH2O: >5 mg/mL, soluble

GHS Safety & Compliance

Flammable / Acute Toxicity / Health HazardSignal word: Danger
  • H225 — Highly flammable liquid and vapour
  • H301 — Toxic if swallowed
  • H311 — Toxic in contact with skin
  • H331 — Toxic if inhaled
  • H370 — Causes damage to organs

Activity & Biological Data

Additional Information[1]. Peters DH, et al. Zonisamide. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in epilepsy. Drugs. 1993 May;45(5):760-87. [2]. Brodie MJ, et al. Zonisamide as adjunctive therapy for refractory partial seizures. Epilepsy Res. 2006 Feb;68 Suppl 2:S11-6. Epub 2005 Nov 28.

Customs & Trade Information

HS Code2935009090
Summary2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Frequently Asked Questions

What is the CAS number of Zonisamide?

The CAS number of Zonisamide is 68291-97-4.

What are the molecular formula and molecular weight of Zonisamide?

Zonisamide has molecular formula C8H8N2O3S and molecular weight 212.226 g/mol.

Is Zonisamide hazardous?

Zonisamide has GHS signal word Danger and hazard statements H225 — Highly flammable liquid and vapour; H301 — Toxic if swallowed; H311 — Toxic in contact with skin.

What are the upstream and downstream products of Zonisamide?

For Zonisamide, Upstream Products: Benzo[d]isoxazol-3-ylmethanesulfonyl chloride, 1,2-Benzisoxazole-3-methanesulfonic acid sodium salt, 2-(1,2-Benzisoxazol-3-yl)acetic acid; Downstream Products: 1,2-Benzisoxazole-3-methanesulfonic acid sodium salt, Salicylic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Zonisamide (CAS 68291-97-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-19269-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.