Metamizole sodium

安乃近

Also known as: Dipyrone, Novalgin, Analgin, Methamizole Sodium, Sodium [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulfonate, Metamizole, Algocalmin, ARPF, Alangin, Anador, Dipyron, Nartate, Novacid, Novil, Sulpin, Unagen, conmel, fevonil, pyretin, pyrojec

Metamizole sodium (CAS 68-89-3) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C13H16N3NaO4S and a molecular weight of 333.339 g/mol. It is also known as Dipyrone, Novalgin and Analgin. Key property: a melting point of 187ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 68-89-3
Jingsj CID: J-1115500-3
Molecular Formula: C₁₃H₁₆N₃NaO₄S
Chinese Name: 安乃近
Molecular Weight: 333.339 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	187ºC
Exact Mass	333.075928
PSA	95.75000
LogP	1.50410
Stability	Stable. Incompatible with strong oxidizing agents.

Activity & Biological Data

Target	COX-3[2]
Additional Information	[1]. A Jasiecka, et al. Pharmacological characteristics of metamizole. Pol J Vet Sci. 2014;17(1):207-14. [2]. N V Chandrasekharan, et al. COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression. Proc Natl Acad Sci U S A. 2002 Oct 15; 99(21): 13926–13931. [3]. Manuela Malsy, et al. Effects of metamizole, MAA, and paracetamol on proliferation, apoptosis, and necrosis in the pancreatic cancer cell lines PaTu 8988 t and Panc-1. BMC Pharmacol Toxicol. 2017 Dec 6;18(1):77. [4]. Renata Zajaczkowska, et al. Metamizole relieves pain by influencing cytokine levels in dorsal root ganglia in a rat model of neuropathic pain. Pharmacol Rep. 2020 Oct;72(5):1310-1322.

Target

COX-3[2]

Additional Information

[1]. A Jasiecka, et al. Pharmacological characteristics of metamizole. Pol J Vet Sci. 2014;17(1):207-14. [2]. N V Chandrasekharan, et al. COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression. Proc Natl Acad Sci U S A. 2002 Oct 15; 99(21): 13926–13931. [3]. Manuela Malsy, et al. Effects of metamizole, MAA, and paracetamol on proliferation, apoptosis, and necrosis in the pancreatic cancer cell lines PaTu 8988 t and Panc-1. BMC Pharmacol Toxicol. 2017 Dec 6;18(1):77. [4]. Renata Zajaczkowska, et al. Metamizole relieves pain by influencing cytokine levels in dorsal root ganglia in a rat model of neuropathic pain. Pharmacol Rep. 2020 Oct;72(5):1310-1322.

Customs & Trade Information

HS Code	2933192000

Frequently Asked Questions

What is the CAS number of Metamizole sodium?

The CAS number of Metamizole sodium is 68-89-3.

What are the molecular formula and molecular weight of Metamizole sodium?

Metamizole sodium has molecular formula C13H16N3NaO4S and molecular weight 333.339 g/mol.

What are the upstream and downstream products of Metamizole sodium?

For Metamizole sodium, Downstream Products: 4-Methylaminoantipyrine, Formaldehyde, 4-Aminoantipyrine.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Metamizole sodium (CAS 68-89-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1115500-3 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.