Metformin
Also known as: 1,1-Dimethylbiguanide, 3-(diaminomethylidene)-1,1-dimethylguanidine, N,N-dimethylbiguanide, N,N-dimethylimidodicarbonimidic diamide, Glucophage, Diabex, Diabetosan, Glumetza, Metforminum, Metiguanide, Fluamine
Metformin (CAS 657-24-9) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C4H11N5 and a molecular weight of 129.16 g/mol. Key properties include a melting point of 199-200 °C, a boiling point of 229.23°C, a density of 1.0743 and a flash point of 58.1±22.6 °C. It is listed by 1 supplier, from 30.08 to 37.60 CNY. Record last updated Aug 21, 2026.
- CAS No.
- 657-24-9
- Jingsj CID
- J-1962917-5
- Molecular Formula
- C4H11N5
- Molecular Weight
- 129.16 g/mol
- Category
- Organic Bases
- Last updated
- 8/21/2026
| Supplier | Purity / Pack | Base Price | Unit Price | Origin | |
|---|---|---|---|---|---|
Made to Order | 99% 25g | ¥752.00 | $4.5 /gBest ¥30.08/g CNY | CN China MOQ 25g | |
Made to Order | 99% 5g | ¥188.00 | $5.63 /g ¥37.60/g CNY | CN China MOQ 5g |
Physicochemical Properties
| Melting Point | 199-200 °C |
|---|---|
| Boiling Point | 229.23°C |
| Density | 1.0743 |
| Flash Point | 58.1±22.6 °C |
| Exact Mass | 129.101440 |
| PSA | 88.99000 |
| LogP | -2.31 |
| Appearance | Solid,White to Light Brown |
| Vapor Pressure | 1.3±0.3 mmHg at 25°C |
| Refractive Index | 1.576 |
| Additional Property | Acetonitrile (Slightly), Aqueous Acid (Slightly), Dichloromethane (Slightly), DM |
| SMILES | CN(C)C(=N)N=C(N)N |
| InChIKey | XZWYZXLIPXDOLR-UHFFFAOYSA-N |
| InChI | 1S/C4H11N5/c1-9(2)4(7)8-3(5)6/h1-2H3,(H5,5,6,7,8) |
Activity & Biological Data
| Target | AMPK |
|---|---|
| Additional Information | [1]. Soraya H, et al. Acute treatment with metformin improves cardiac function following isoproterenol induced myocardial infarction in rats. Pharmacol Rep. 2012;64(6):1476-84. [2]. Quaile MP, et al. Toxicity and toxicokinetics of metformin in rats. Toxicol Appl Pharmacol. 2010 Mar 15;243(3):340-7. [3]. Xue J, et al. Metformin inhibits growth of eutopic stromal cells from adenomyotic endometrium via AMPK activation and subsequent inhibition of AKT phosphorylation: a possible role in the treatment of adenomyosis. Reproduction. 2013 Aug 21;146(4):397-406. [4]. Otto M, et al. Metformin inhibits glycogen synthesis and gluconeogenesis in cultured rat hepatocytes. Diabetes Obes Metab. 2003 May;5(3):189-94. [5]. Avci CB, et al. Therapeutic potential of an anti-diabetic drug, metformin: alteration of miRNA expression in prostate cancer cells. Asian Pac J Cancer Prev. 2013;14(2):765-8. |
Frequently Asked Questions
What is the CAS number of Metformin?
The CAS number of Metformin is 657-24-9.
What are the molecular formula and molecular weight of Metformin?
Metformin has molecular formula C4H11N5 and molecular weight 129.16 g/mol.
Which suppliers offer Metformin?
1 supplier(s) listed; reference unit price ¥30.08–37.60 /g.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Metformin (CAS 657-24-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1962917-5 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.