Nicorandil
尼可地尔
Also known as: 2-Nicotinamidoethyl nitrate, N-[2-(Nitroxy)ethyl]-3-pyridinecarboxamide, N-[2-(Nitrooxy)ethyl]-3-pyridinecarboxamide, N-(2-Hydroxyethyl)nicotinamide nitrate ester, 2-[(Pyridin-3-ylcarbonyl)amino]ethyl nitrate, SG-75, Ikorel, Sigmart, Dancor, Adancor, Perisalol, Nikoran, Nicorandilum, EINECS 265-514-1
Nicorandil (CAS 65141-46-0) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C8H9N3O4 and a molecular weight of 211.175 g/mol. It is also known as 2-Nicotinamidoethyl nitrate, N-[2-(Nitroxy)ethyl]-3-pyridinecarboxamide and N-[2-(Nitrooxy)ethyl]-3-pyridinecarboxamide. Key properties include a melting point of 92ºC, a boiling point of 456.7±25.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 230.0±23.2 °C. It is classified under GHS with signal word Danger and hazard statements H302 — Harmful if swallowed and H318 — Causes serious eye damage. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 65141-46-0
- Jingsj CID
- J-48505-2
- Molecular Formula
- C8H9N3O4
- Chinese Name
- 尼可地尔
- Molecular Weight
- 211.175 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 92ºC |
|---|---|
| Boiling Point | 456.7±25.0 °C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 230.0±23.2 °C |
| Exact Mass | 211.059311 |
| PSA | 97.04000 |
| LogP | 0.72 |
| Vapor Pressure | 0.0±1.1 mmHg at 25°C |
| Refractive Index | 1.548 |
GHS Safety & Compliance
- H302 — Harmful if swallowed
- H318 — Causes serious eye damage
Activity & Biological Data
| Additional Information | [1]. Nakae, I., et al., Effects of intravenous nicorandil on coronary circulation in humans: plasma concentration and action mechanism. J Cardiovasc Pharmacol, 2000. 35(6): p. 919-25. [2]. Sauzeau, V., et al., Cyclic GMP-dependent protein kinase signaling pathway inhibits RhoA-induced Ca2+ sensitization of contraction in vascular smooth muscle. J Biol Chem, 2000. 275(28): p. 21722-9. |
|---|
Customs & Trade Information
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Nicorandil?
The CAS number of Nicorandil is 65141-46-0.
What are the molecular formula and molecular weight of Nicorandil?
Nicorandil has molecular formula C8H9N3O4 and molecular weight 211.175 g/mol.
Is Nicorandil hazardous?
Nicorandil has GHS signal word Danger and hazard statements H302 — Harmful if swallowed; H318 — Causes serious eye damage.
What are the upstream and downstream products of Nicorandil?
For Nicorandil, Upstream Products: Nicotinoyl chloride hydrochloride, N-(2-hydroxyethyl)nicotinamide; Downstream Products: Pyridine, 3-(4,5-dihydro-2-oxazolyl)-, N-(2-hydroxyethyl)nicotinamide.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Nicorandil (CAS 65141-46-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-48505-2 (accessed 2026-10-28).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.