Yohimbine hydrochloride

Also known as: Yohimbine HCl, Yohimbe HCl, Corynine hydrochloride, Aphrodine hydrochloride, Querbrachine, Yohimbine monohydrochloride, Methyl (16α,17α)-17-hydroxyyohimban-16-carboxylate hydrochloride, Methyl (1R,2S,4aR,13bS,14aS)-2-hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate hydrochloride, 17-Hydroxyyohimban-16-carboxylic acid methyl ester hydrochloride, UNII-NB2E1YP49F

Yohimbine hydrochloride (CAS 65-19-0) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C21H27ClN2O3 and a molecular weight of 390.904 g/mol. Key properties include a melting point of 288-290 °C (dec.)(lit.), a boiling point of 542.979ºC at 760 mmHg and a flash point of 282.184ºC. It is classified under GHS with signal word Danger and hazard statements H300, H311 — Toxic in contact with skin and H331 — Toxic if inhaled. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 65-19-0
Jingsj CID: J-37944-7
Molecular Formula: C₂₁H₂₇ClN₂O₃
Molecular Weight: 390.904 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	288-290 °C (dec.)(lit.)
Boiling Point	542.979ºC at 760 mmHg
Flash Point	282.184ºC
Exact Mass	390.171021
PSA	65.56000
LogP	3.38700
Refractive Index	103 ° (C=1, H2O)

GHS Safety & Compliance

Acute ToxicitySignal word: Danger

H300
H311 — Toxic in contact with skin
H331 — Toxic if inhaled

Activity & Biological Data

Additional Information	[1]. Saad MA, et al. Potential effects of yohimbine and sildenafil on erectile dysfunction in rats. [2]. Docherty JR. Yohimbine antagonises α1A- and α1D-adrenoceptor mediated components in addition to the α2A-adrenoceptor component to pressor responses in the pithed rat. Eur J Pharmacol. 2012 Mar 15;679(1-3):90-4. [3]. Lahiri P, et al. Platelet responsiveness to yohimbine hydrochloride and MRS2179 in the context of the interaction between collagen and epinephrine in acute coronary syndrome. Blood Cells Mol Dis. 2009 Jul-Aug;43(1):105-10.

Additional Information

[1]. Saad MA, et al. Potential effects of yohimbine and sildenafil on erectile dysfunction in rats. [2]. Docherty JR. Yohimbine antagonises α1A- and α1D-adrenoceptor mediated components in addition to the α2A-adrenoceptor component to pressor responses in the pithed rat. Eur J Pharmacol. 2012 Mar 15;679(1-3):90-4. [3]. Lahiri P, et al. Platelet responsiveness to yohimbine hydrochloride and MRS2179 in the context of the interaction between collagen and epinephrine in acute coronary syndrome. Blood Cells Mol Dis. 2009 Jul-Aug;43(1):105-10.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Yohimbine hydrochloride?

The CAS number of Yohimbine hydrochloride is 65-19-0.

What are the molecular formula and molecular weight of Yohimbine hydrochloride?

Yohimbine hydrochloride has molecular formula C21H27ClN2O3 and molecular weight 390.904 g/mol.

Is Yohimbine hydrochloride hazardous?

Yohimbine hydrochloride has GHS signal word Danger and hazard statements H300; H311 — Toxic in contact with skin; H331 — Toxic if inhaled.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Yohimbine hydrochloride (CAS 65-19-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-37944-7 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.