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3,4-Dimethoxycinnamonitrile

Also known as: 3,4-Dimethoxycinnamonitrile, (2E)-3-(3,4-dimethoxyphenyl)acrylonitrile, (E)-3-(3,4-dimethoxyphenyl)prop-2-enenitrile, 2-Propenenitrile, 3-(3,4-dimethoxyphenyl)-, (2E)-, 3-(3,4-Dimethoxyphenyl)acrylonitrile, β-(3,4-Dimethoxyphenyl)acrylonitrile, Donepezil Intermediate 21

3,4-Dimethoxycinnamonitrile (CAS 6443-72-7) is a compound in the Nitrogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C11H11NO2 and a molecular weight of 189.210 g/mol. Key properties include a melting point of 181-184ºC, a boiling point of 339.2±27.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 134.3±16.9 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed, H312 — Harmful in contact with skin and H332 — Harmful if inhaled. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
6443-72-7
Jingsj CID
J-6635-3
Molecular Formula
C11H11NO2
Molecular Weight
189.210 g/mol
Category
Nitrogen Compounds
Last updated
8/21/2026

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Physicochemical Properties

Melting Point181-184ºC
Boiling Point339.2±27.0 °C at 760 mmHg
Density1.1±0.1 g/cm3
Flash Point134.3±16.9 °C
Exact Mass189.078979
PSA42.25000
LogP2.15
Vapor Pressure0.0±0.7 mmHg at 25°C
Refractive Index1.558

GHS Safety & Compliance

IrritantSignal word: Warning
  • H302 — Harmful if swallowed
  • H312 — Harmful in contact with skin
  • H332 — Harmful if inhaled

Customs & Trade Information

HS Code2926909090
SummaryHS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 3,4-Dimethoxycinnamonitrile?

The CAS number of 3,4-Dimethoxycinnamonitrile is 6443-72-7.

What are the molecular formula and molecular weight of 3,4-Dimethoxycinnamonitrile?

3,4-Dimethoxycinnamonitrile has molecular formula C11H11NO2 and molecular weight 189.210 g/mol.

Is 3,4-Dimethoxycinnamonitrile hazardous?

3,4-Dimethoxycinnamonitrile has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H312 — Harmful in contact with skin; H332 — Harmful if inhaled.

What are the upstream and downstream products of 3,4-Dimethoxycinnamonitrile?

For 3,4-Dimethoxycinnamonitrile, Upstream Products: Veratraldehyde, Cyanoacetic acid, (Triphenylphosphoranylidene)acetonitrile; Downstream Products: 3-(3,4-Dimethoxyphenyl)propan-1-amine, Annuloline.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "3,4-Dimethoxycinnamonitrile (CAS 6443-72-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-6635-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.