Clofibrate
Also known as: Ethyl 2-(4-chlorophenoxy)-2-methylpropionate, Ethyl 2-(4-chlorophenoxy)isobutyrate, Ethyl α-(4-chlorophenoxy)-α-methylpropionate, Ethyl α-(4-chlorophenoxy)isobutyrate, Ethyl p-chlorophenoxyisobutyrate, 2-(p-Chlorophenoxy)-2-methylpropionic acid ethyl ester, 2-(4-Chlorophenoxy)isobutyric acid ethyl ester, Atromid-S, Atromid, Clofibric acid ethyl ester, CPIB, Lipavlon, Regelan, Sklerolip, Abitrate, Amotril, Anparton, Antilipid, Arterioflexin, Ateculon
Clofibrate (CAS 637-07-0) is a compound in the Esters category listed in the Jingsj chemical database. It has the molecular formula C12H15ClO3 and a molecular weight of 242.699 g/mol. Key properties include a boiling point of 274.8±0.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 115.1±19.9 °C. It is classified under GHS with signal word Danger and hazard statements H302 — Harmful if swallowed, H315 — Causes skin irritation and H318 — Causes serious eye damage. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 637-07-0
- Jingsj CID
- J-45279-7
- Molecular Formula
- C12H15ClO3
- Molecular Weight
- 242.699 g/mol
- Category
- Esters
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Boiling Point | 274.8±0.0 °C at 760 mmHg |
|---|---|
| Density | 1.1±0.1 g/cm3 |
| Flash Point | 115.1±19.9 °C |
| Exact Mass | 242.070969 |
| PSA | 35.53000 |
| LogP | 3.32 |
| Vapor Pressure | 0.0±0.5 mmHg at 25°C |
| Refractive Index | 1.505 |
GHS Safety & Compliance
- H302 — Harmful if swallowed
- H315 — Causes skin irritation
- H318 — Causes serious eye damage
- H335 — May cause respiratory irritation
Activity & Biological Data
| Target | PPARα:50 μM (EC50) PPARγ:500 μM (EC50) |
|---|---|
| Additional Information | [1]. Willson TM, et al. The PPARs: from orphan receptors to drug discovery. J Med Chem. 2000 Feb 24;43(4):527-50. [2]. Chen Y, et al. Clofibrate Attenuates ROS Production by Lipid Overload in Cultured Rat Hepatoma Cells. J Pharm Pharm Sci. 2017;20(0):239-251. [3]. Chen SH, et al. Prenatal PPARα activation by clofibrate increases subcutaneous fat browning in male C57BL/6J mice fed a high-fat diet during adulthood. PLoS One. 2017 Nov 2;12(11):e0187507. |
Customs & Trade Information
| HS Code | 2918990090 |
|---|---|
| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of Clofibrate?
The CAS number of Clofibrate is 637-07-0.
What are the molecular formula and molecular weight of Clofibrate?
Clofibrate has molecular formula C12H15ClO3 and molecular weight 242.699 g/mol.
Is Clofibrate hazardous?
Clofibrate has GHS signal word Danger and hazard statements H302 — Harmful if swallowed; H315 — Causes skin irritation; H318 — Causes serious eye damage.
What are the upstream and downstream products of Clofibrate?
For Clofibrate, Upstream Products: Ethyl 2-bromoisobutyrate, 4-Chlorophenol, Ethanol; Downstream Products: Clofibric acid, Ethanol.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Clofibrate (CAS 637-07-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-45279-7 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.