Staurosporine
星形孢菌素
Also known as: STS, AM-2282, Antibiotic AM-2282, Antibiotic 230, Antibiotic M 193, CGP 39360, STSP, Staurosporin, Stauroporine, MFCD00077402, (9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one
Staurosporine (CAS 62996-74-1) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C28H26N4O3 and a molecular weight of 466.531 g/mol. It is also known as STS, AM-2282 and Antibiotic AM-2282. Key properties include a melting point of 270ºC, a boiling point of 677.5±55.0 °C at 760 mmHg, a density of 1.6±0.1 g/cm3 and a flash point of 363.6±31.5 °C. It is classified under GHS with signal word Danger and hazard statements H340 and H350 — May cause cancer. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 62996-74-1
- Jingsj CID
- J-7751-0
- Molecular Formula
- C28H26N4O3
- Chinese Name
- 星形孢菌素
- Molecular Weight
- 466.531 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 270ºC |
|---|---|
| Boiling Point | 677.5±55.0 °C at 760 mmHg |
| Density | 1.6±0.1 g/cm3 |
| Flash Point | 363.6±31.5 °C |
| Exact Mass | 466.200500 |
| PSA | 69.45000 |
| LogP | 4.40 |
| Vapor Pressure | 0.0±2.1 mmHg at 25°C |
| Refractive Index | 1.810 |
GHS Safety & Compliance
- H340
- H350 — May cause cancer
Activity & Biological Data
| Target | PKC:6 nM (IC50) c-Fgr:2 nM (IC50) Phosphorylase kinase:3 nM (IC50) v-Src:6 nM (IC50) cdc2:9 nM (IC50) TPK-IIB/Syk:16 nM (IC50) Ca2+/CaM PK-I1:20 nM (IC50) MLCK:21 nM (IC50) IR:61 nM (IC50) EGF-R:100 nM (IC50) ERK-1:1500 nM (IC50) CSK:2000 nM (IC50) IGF-IR:6150 nM (IC50) CK2:19500 nM (IC50) CK1:163500 nM (IC50) S6 kinase (70 kDa):5 nM (IC50) PKA:15 nM (IC50) |
|---|---|
| Additional Information | [1]. Meggio F, et al. Different susceptibility of protein kinases to staurosporine inhibition. Kinetic studies and molecular bases for the resistance of protein kinase CK2. Eur J Biochem. 1995 Nov 15;234(1):317-22. [2]. Chae HJ, et al. Molecular mechanism of staurosporine-induced apoptosis in osteoblasts. Pharmacol Res. 2000 Oct;42(4):373-81. [3]. Yoshizawa S, et al. Tumor-promoting activity of staurosporine, a protein kinase inhibitor on mouse skin.Cancer Res. 1990 Aug 15;50(16):4974-8. [4]. Nabeshima T, et al. Staurosporine facilitates recovery from the basal forebrain-lesion-induced impairment of learning and deficit of cholinergic neuron in rats. J Pharmacol Exp Ther. 1991 May;257(2):562-6. |
Frequently Asked Questions
What is the CAS number of Staurosporine?
The CAS number of Staurosporine is 62996-74-1.
What are the molecular formula and molecular weight of Staurosporine?
Staurosporine has molecular formula C28H26N4O3 and molecular weight 466.531 g/mol.
Is Staurosporine hazardous?
Staurosporine has GHS signal word Danger and hazard statements H340; H350 — May cause cancer.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Staurosporine (CAS 62996-74-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-7751-0 (accessed 2026-10-28).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.