Protopine hydrochloride
盐酸普罗托平
Also known as: Protopine HCl, Protopine hydrochloride, Fumarine hydrochloride, Macleyine hydrochloride, Bis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-13(5H)-one, 4,6,7,14-tetrahydro-5-methyl-, hydrochloride (1:1), 13a-secoberbin-13a-one, 7-methyl-2,3:9,10-bis(methylenedioxy)-, hydrochloride, EINECS 228-196-5, MFCD00236406
Protopine hydrochloride (CAS 6164-47-2) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C20H20ClNO5 and a molecular weight of 389.83 g/mol. It is also known as Protopine HCl, Fumarine hydrochloride and Macleyine hydrochloride. Key properties include a melting point of 208ºC, a boiling point of 547.5ºC at 760 mmHg and a flash point of 284.9ºC. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 6164-47-2
- Jingsj CID
- J-35635-2
- Molecular Formula
- C20H20ClNO5
- Chinese Name
- 盐酸普罗托平
- Molecular Weight
- 389.83 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 208ºC |
|---|---|
| Boiling Point | 547.5ºC at 760 mmHg |
| Flash Point | 284.9ºC |
| Exact Mass | 389.10300 |
| PSA | 57.23000 |
| LogP | 3.29720 |
GHS Safety & Compliance
- H301 — Toxic if swallowed
Activity & Biological Data
| Additional Information | [1]. Kim SR, et, al. Protopine from Corydalis ternata has anticholinesterase and antiamnesic activities. Planta Med. 1999 Apr;65(3):218-21. [2]. Nie C, et, al. Protopine triggers apoptosis via the intrinsic pathway and regulation of ROS/PI3K/Akt signalling pathway in liver carcinoma. Cancer Cell Int. 2021 Jul 27;21(1):396. |
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Frequently Asked Questions
What is the CAS number of Protopine hydrochloride?
The CAS number of Protopine hydrochloride is 6164-47-2.
What are the molecular formula and molecular weight of Protopine hydrochloride?
Protopine hydrochloride has molecular formula C20H20ClNO5 and molecular weight 389.83 g/mol.
Is Protopine hydrochloride hazardous?
Protopine hydrochloride has GHS signal word Danger and hazard statements H301 — Toxic if swallowed.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Protopine hydrochloride (CAS 6164-47-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-35635-2 (accessed 2026-10-28).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.