Cefotiam

头孢替安

Also known as: 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)acetyl]amino]-3-[[[1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl]thio]methyl]-8-oxo-, (6R,7R)-, (6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)acetyl]amino]-3-[[1-[2-(dimethylamino)ethyl]tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, CGP 14221E, SCE 963, Cefotiamum

Cefotiam (CAS 61622-34-2) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C18H23N9O4S3 and a molecular weight of 525.628 g/mol. It is also known as 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)acetyl]amino]-3-[[[1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl]thio]methyl]-8-oxo-, (6R,7R)-, (6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)acetyl]amino]-3-[[1-[2-(dimethylamino)ethyl]tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid and CGP 14221E. Key property: a density of 1.8±0.1 g/cm3. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
61622-34-2
Jingsj CID
J-49248-7
Molecular Formula
C18H23N9O4S3
Chinese Name
头孢替安
Molecular Weight
525.628 g/mol
Category
Organic Compounds
Last updated
8/21/2026

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Physicochemical Properties

Density1.8±0.1 g/cm3
Exact Mass525.103516
PSA251.30000
LogP0.24
Refractive Index1.855
Additional PropertySoluble

Activity & Biological Data

TargetMIC: 1.56 μg/mL (bacterial)
Additional Information[1]. Yumi Hashiguchi, et al. Clinical evaluation of cefotiam in the treatment of bacteremia caused by Escherichia coli, Klebsiella species, and Proteus mirabilis: A retrospective study. J Infect Chemother. 2020 Nov;26(11):1158-1163. [2]. T Iwahi, et al. Comparative activities of cefotiam and cefazolin against urinary tract infections with Proteus mirabilis in mice. Antimicrob Agents Chemother [3]. Kazuhiro Ishizaka, et al. Randomized prospective comparison of fosfomycin and cefotiam for prevention of postoperative infection following urological surgery. J Infect Chemother. 2007 Oct;13(5):324-31.

Frequently Asked Questions

What is the CAS number of Cefotiam?

The CAS number of Cefotiam is 61622-34-2.

What are the molecular formula and molecular weight of Cefotiam?

Cefotiam has molecular formula C18H23N9O4S3 and molecular weight 525.628 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Cefotiam (CAS 61622-34-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-49248-7 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.