Prostratin

12-脱氧佛波醇-13-乙酸

Also known as: 12-Deoxyphorbol 13-acetate, 12-Deoxyphorbol-13-acetate, 13-O-Acetyl-12-deoxyphorbol, 13-O-Acetylphorbol, dPAc, NSC 623310, SA 101A, Stillingia factor S7, Stillingia Facto, (1aR,1bS,4aR,7aS,7bR,8R,9aS)-9a-(Acetyloxy)-1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one, 12-deoxyphorbal-13-acetate

Prostratin (CAS 60857-08-1) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C22H30O6 and a molecular weight of 390.470 g/mol. It is also known as 12-Deoxyphorbol 13-acetate, 12-Deoxyphorbol-13-acetate and 13-O-Acetyl-12-deoxyphorbol. Key properties include a melting point of 216-219℃, a boiling point of 550.5±50.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 188.7±23.6 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 60857-08-1
Jingsj CID: J-45261-8
Molecular Formula: C₂₂H₃₀O₆
Chinese Name: 12-脱氧佛波醇-13-乙酸
Molecular Weight: 390.470 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	216-219℃
Boiling Point	550.5±50.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	188.7±23.6 °C
Exact Mass	390.204254
PSA	104.06000
LogP	1.84
Vapor Pressure	0.0±3.4 mmHg at 25°C
Refractive Index	1.600
Additional Property	Soluble in DMSO at 30mg/ml

Activity & Biological Data

Target	PKC:12.5 nM (Ki) HIV-1
Additional Information	[1]. Gustafson KR, et al. A nonpromoting phorbol from the samoan medicinal plant Homalanthus nutans inhibits cell killing by HIV-1. J Med Chem. 1992 May 29;35(11):1978-86. [2]. Shen X, et al. The protein kinase C agonist prostratin induces differentiation of human myeloid leukemia cells and enhances cellular differentiation by chemotherapeutic agents. Cancer Lett. 2015 Jan 28;356(2 Pt B):686-96. [3]. Wang H, et al. Protein kinase D3 is essential for prostratin-activated transcription of integrated HIV-1 provirus promoter via NF-κB signaling pathway. Biomed Res Int. 2014;2014:968027.

Target

PKC:12.5 nM (Ki) HIV-1

Additional Information

[1]. Gustafson KR, et al. A nonpromoting phorbol from the samoan medicinal plant Homalanthus nutans inhibits cell killing by HIV-1. J Med Chem. 1992 May 29;35(11):1978-86. [2]. Shen X, et al. The protein kinase C agonist prostratin induces differentiation of human myeloid leukemia cells and enhances cellular differentiation by chemotherapeutic agents. Cancer Lett. 2015 Jan 28;356(2 Pt B):686-96. [3]. Wang H, et al. Protein kinase D3 is essential for prostratin-activated transcription of integrated HIV-1 provirus promoter via NF-κB signaling pathway. Biomed Res Int. 2014;2014:968027.

Frequently Asked Questions

What is the CAS number of Prostratin?

The CAS number of Prostratin is 60857-08-1.

What are the molecular formula and molecular weight of Prostratin?

Prostratin has molecular formula C22H30O6 and molecular weight 390.470 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Prostratin (CAS 60857-08-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-45261-8 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.