Megestrol acetate
Also known as: 17α-Acetoxy-6-methylpregna-4,6-diene-3,20-dione, 6-Methyl-3,20-dioxopregna-4,6-dien-17-yl acetate, 17-(Acetyloxy)-6-methylpregna-4,6-diene-3,20-dione, Megestrol acetate (USAN), Megace, Maygace, Niagestin, Ovarid, Volidan, 6-Dehydro-6-methyl-17α-acetoxyprogesterone, 17α-Acetoxy-6-methyl-4,6-pregnadiene-3,20-dione, Pregna-4,6-diene-3,20-dione, 17-(acetyloxy)-6-methyl-, (8R,9S,10R,13S,14S,17R)-17-Acetyl-6,10,13-trimethyl-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate
Megestrol acetate (CAS 595-33-5) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C24H32O4 and a molecular weight of 384.509 g/mol. Key properties include a melting point of 214°C, a boiling point of 507.1±50.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 218.5±30.2 °C. It is classified under GHS with signal word Warning and hazard statements H351 — Suspected of causing cancer and H373 — May cause damage to organs through prolonged exposure. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 595-33-5
- Jingsj CID
- J-15079-2
- Molecular Formula
- C24H32O4
- Molecular Weight
- 384.509 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 214°C |
|---|---|
| Boiling Point | 507.1±50.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 218.5±30.2 °C |
| Exact Mass | 384.230072 |
| PSA | 60.44000 |
| LogP | 3.82 |
| Vapor Pressure | 0.0±1.3 mmHg at 25°C |
| Refractive Index | 1.551 |
| Storage Conditions | Refrigerator |
GHS Safety & Compliance
- H351 — Suspected of causing cancer
- H373 — May cause damage to organs through prolonged exposure
Activity & Biological Data
| Additional Information | [1]. Neumann, F., The physiological action of progesterone and the pharmacological effects of progestogens--a short review. Postgrad Med J, 1978. 54 Suppl 2: p. 11-24. [2]. Argiles, J.M., A. Anguera, and B. Stemmler, A new look at an old drug for the treatment of cancer cachexia: megestrol acetate. Clin Nutr, 2013. 32(3): p. 319-24. |
|---|
Frequently Asked Questions
What is the CAS number of Megestrol acetate?
The CAS number of Megestrol acetate is 595-33-5.
What are the molecular formula and molecular weight of Megestrol acetate?
Megestrol acetate has molecular formula C24H32O4 and molecular weight 384.509 g/mol.
Is Megestrol acetate hazardous?
Megestrol acetate has GHS signal word Warning and hazard statements H351 — Suspected of causing cancer; H373 — May cause damage to organs through prolonged exposure.
What are the upstream and downstream products of Megestrol acetate?
For Megestrol acetate, Upstream Products: 17-hydroxy-6-methylenepregn-4-ene-3,20-dione 17-acetate, Medroxyprogesterone acetate, Medroxyprogesterone; Downstream Products: Megestrol.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Megestrol acetate (CAS 595-33-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-15079-2 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.