Procaine

普鲁卡因

Also known as: Novocaine, Novocain, 2-(Diethylamino)ethyl 4-aminobenzoate, 4-Aminobenzoic acid 2-(diethylamino)ethyl ester, Procaine Base, β-Diethylaminoethyl p-aminobenzoate

Procaine (CAS 59-46-1) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C13H20N2O2 and a molecular weight of 236.310 g/mol. It is also known as Novocaine, Novocain and 2-(Diethylamino)ethyl 4-aminobenzoate. Key properties include a melting point of 61ºC, a boiling point of 373.6±22.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 179.8±22.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 59-46-1
Jingsj CID: J-1959620-2
Molecular Formula: C₁₃H₂₀N₂O₂
Chinese Name: 普鲁卡因
Molecular Weight: 236.310 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	61ºC
Boiling Point	373.6±22.0 °C at 760 mmHg
Density	1.1±0.1 g/cm3
Flash Point	179.8±22.3 °C
Exact Mass	236.152481
PSA	55.56000
LogP	2.36
Vapor Pressure	0.0±0.8 mmHg at 25°C
Refractive Index	1.543

Activity & Biological Data

Additional Information	[1]. Fan, P. and F.F. Weight, Procaine impairs the function of 5-HT3 receptor-ion channel complex in rat sensory ganglion neurons. Neuropharmacology, 1994. 33(12): p. 1573-9. [2]. Villar-Garea, A., et al., Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells. Cancer Res, 2003. 63(16): p. 4984-9. [3]. Adamec, R.E. and C. Stark-Adamec, The effects of procaine HCl on population cellular and evoked response activity within the limbic system of the cat. Evidence for differential excitatory action of procaine in a variety of limbic circuits. Prog Neuropsychopharmacol Biol Psychiatry, 1987. 11(4): p. 345-64.

Additional Information

[1]. Fan, P. and F.F. Weight, Procaine impairs the function of 5-HT3 receptor-ion channel complex in rat sensory ganglion neurons. Neuropharmacology, 1994. 33(12): p. 1573-9. [2]. Villar-Garea, A., et al., Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells. Cancer Res, 2003. 63(16): p. 4984-9. [3]. Adamec, R.E. and C. Stark-Adamec, The effects of procaine HCl on population cellular and evoked response activity within the limbic system of the cat. Evidence for differential excitatory action of procaine in a variety of limbic circuits. Prog Neuropsychopharmacol Biol Psychiatry, 1987. 11(4): p. 345-64.

Customs & Trade Information

HS Code	2922499990
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Procaine?

The CAS number of Procaine is 59-46-1.

What are the molecular formula and molecular weight of Procaine?

Procaine has molecular formula C13H20N2O2 and molecular weight 236.310 g/mol.

What are the upstream and downstream products of Procaine?

For Procaine, Upstream Products: Ethyl 4-nitrobenzoate, 2-(Diethylamino)ethanol, Methyl 4-aminobenzoate; Downstream Products: Procaine penicillin G, 4-aminobenzoic acid, 2-(Diethylamino)ethanol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Procaine (CAS 59-46-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1959620-2 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.